II. Updates: April 2024
-
Accelerated Idioventricular Rhythm (cv, ekg)
- Added
-
Brugada Syndrome (cv, ekg)
- Updates
-
Resistant Hypertension (cv, htn)
- Updates
-
Hypertensive Disorders of Pregnancy (cv, ob)
- Extensive Updates
-
Diabetic Foot Infection (derm, endo)
- Updates
-
Tape Strip Melanoma Detection (derm, lab)
- Added
-
Diabetic Ketoacidosis Management in Children (endo, dm)
- Updates
-
Diabetic Neuropathy (endo, neuro)
- Updates
-
Nasal Foreign Body (ent, nose)
- Updates
-
Hearing Aid (ent, pharm)
- Updates
-
Pediatric Trauma (er, peds)
- Updates, including Pediatric Abdominal Trauma
-
Penetrating Trauma (er, Trauma)
- Updates
-
Pediatric Blunt Abdominal Trauma Decision Rule (gi, exam)
- Updates
-
Pancreatic Cancer (gi, hemeonc)
- Updates
-
Carbohydrate
Antigen 19-9 (gi, lab)
- Updates
-
Lower Gastrointestinal Bleeding (gi, sx)
- Updates
-
Fezolinetant (gyn, pharm)
- Updates
-
ASCCP Calculated Risk Based Protocol (gyn, prevent)
- Updates
-
IgA Vasculitis (hemeonc, derm)
- Updates
-
Juvenile Xanthogranuloma (hemeonc, marrow)
- Added
- Checkpoint Inhibitor (hemeonc, pharm)
- Updates
-
Antiplatelet Therapy in CVA and TIA (hemeonc, pharm)
- Updates
-
Mitosis Inhibitor
Chemotherapy (hemeonc, pharm)
- Added Vinca Alkaloids, Taxanes and Topoisomerase Inhibitors
- Also added Ixabepilone, Eribulin
-
Vinca Alkaloids (hemeonc, pharm)
- Added Vinblastine (Velban), Vincristine (Oncovin), Vinorelbine
-
Taxanes (hemeonc, pharm)
- Added Paclitaxel (Taxol), Albumin-Bound Paclitaxel (Abraxane), Docetaxel (Taxotere), Cabazitaxel (Jevtana)
-
Topoisomerase Inhibitor (hemeonc, pharm)
- Added Topotecan, Irinotecan, Irinotecan Liposome, Etoposide
-
Arsenic Trioxide (hemeonc, pharm)
- Added as a antineoplastic
-
Cytarabine (hemeonc, pharm)
- Added
-
Bleomycin (hemeonc, pharm)
- Added
-
Dactinomycin (hemeonc, pharm)
- Added
-
Daunorubicin (hemeonc, pharm)
- Added
-
Decitabine (hemeonc, pharm)
- Added
-
Floxuridine (hemeonc, pharm)
- Added
-
Fludarabine (hemeonc, pharm)
- Added
-
Fluorouracil (hemeonc, pharm)
- Added
-
Gemcitabine (hemeonc, pharm)
- Added
-
Proteasome Inhibitor (hemeonc, pharm)
- Added
-
Systemic Tretinoin (hemeonc, pharm)
- Added, as antineoplastic agent
-
Trifluridine-Tipiracil (hemeonc, pharm)
- Added
-
Histone Deacetylase Inhibitor (hemeonc, pharm)
- Added individual agent entries for the 4 drugs in class
-
Hydroxyurea (hemeonc, pharm)
- Updates for use as antineoplastic
-
Mercaptopurine (hemeonc, pharm)
- Added
-
Nelarabine (hemeonc, pharm)
- Added
-
Pentostatin (hemeonc, pharm)
- Added
-
Thioguanine (hemeonc, pharm)
- Added
-
Pemetrexed (hemeonc, pharm)
- Added
-
Pralatrexate (hemeonc, pharm)
- Added
-
Doxorubicin (hemeonc, pharm)
- Added
-
Liposomal Doxorubicin (hemeonc, pharm)
- Added
-
Idarubicin (hemeonc, pharm)
- Added
-
Epirubicin (hemeonc, pharm)
- Added
-
Valrubicin (hemeonc, pharm)
- Added
-
Mitomycin (hemeonc, pharm)
- Added
-
Mitoxantrone (hemeonc, pharm)
- Added
-
Congenital Candida (id, fungus)
- Added
-
Measles (id, virus)
- Updates
-
Lumbar Puncture (neuro, procedure)
- Updates
-
Cutaneous Signs of Dysraphism (nicu, derm)
- Updates
-
Newborn Skin Exam (nicu, exam)
- Updates
-
Prosthetic Knee Arthrocentesis (ortho, procedure)
- Updates
-
Chronic Low Back Pain (ortho, Sx, L-Spine)
- Added
-
Acetaminophen Overdose (pharm, Analgesic)
- Updates
-
Ginger (pharm, alternative)
- Updates
-
Human Trafficking (prevent, abuse)
- Updates
-
Tianeptine (psych, pharm)
- Added
-
Hyperkalemia (renal, Potassium)
- Updates
III. Updates: March 2024
-
Abnormal Uterine Bleeding Associated with Hormonal Contraception (gyn, pharm)
- Updates including management of AUB for various contraceptive options
-
Atrial Fibrillation Acute Management (cv, ekg)
- Updates regarding case reports of self-cardioversion with aerobic Exercise in endurance athletes
- Thanks to my friend, Chris Amley for forwarding the article
-
Cellulitis (derm, Bacteria)
- Updates
-
ACE inhibitor Induced Angioedema (ent, derm)
- Updates regarding ARB after ACE-related Angioedema (ARBs are no longer contraindicated)
-
G-Tube (gi, procedure)
- Updates
-
CT Angiography in Gastrointestinal Bleeding (gi, rad)
- Updates
-
Diabetes Mellitus Control in Hospital (endo, dm)
- Updates
-
DVT Prophylaxis (hemeonc, prevent)
- Updates
-
Azacitidine (hemeonc, pharm)
- Added
-
Alkylating Agent (hemeonc, pharm)
- Updates
-
Anal Fissure (gi, Rectum)
- Updates
-
Artesunate (id, pharm)
- Updates
-
Atovaquone/Proguanil (id, pharm)
- Updates
-
Belinostat (hemeonc, pharm)
- Added
-
Bendamustine (hemeonc, pharm)
- Added
-
Benznidazole (id, Pharm)
- Added
-
Busulfan (hemeonc, pharm)
- Added
-
Capecitabine (hemeonc, pharm)
- Added
-
Carmustine (hemeonc, pharm)
- Added
-
Chlorambucil (hemeonc, pharm)
- Added
-
Chloroquine (id, pharm)
- Added
-
Cladribine (hemeonc, pharm)
- Added
-
Clofarabine (hemeonc, pharm)
- Added
-
Coartem (id, pharm)
- Added
-
Cyclophosphamide (hemeonc, pharm)
- Added
-
Dacarbazine (hemeonc, pharm)
- Added
-
DIP Dislocation (ortho, hand)
- Updates
-
Dizziness (cv, sx)
- Added image of differential Diagnosis
-
Eating Disorder (psych, eating)
- Updates
-
Foot Fracture (ortho, foot)
- Extensive updates to various Fractures of the foot
-
Hordeolum (eye, lid)
- Updates
-
Ifosfamide (hemeonc, pharm)
- Added
-
Insomnia (psych, sleep)
- Updates
-
Lipoprotein A
- Added (cv, lab)
-
Lomustine (hemeonc, pharm)
- Added
-
Mechlorethamine (hemeonc, pharm)
- Added
-
Methotrexate (hemeonc, pharm)
- Updates
-
Monomorphic Ventricular Tachycardia (cv, ekg)
- Updates
-
Ivermectin (id, Pharm)
- Updates
-
Measles (id, virus)
- Updates
-
Mebendazole (id, Pharm)
- Added
-
Mefloquine (id, pharm)
- Updates
-
Melphalan (hemeonc, pharm)
- Added
-
Miltefosine (id, Pharm)
- Added
-
Moxidectin (id, pharm)
- Added
-
Mumps (id, virus)
- Updates
-
Nitazoxanide (id, pharm)
- Added
-
Paromomycin (id, pharm)
- Added
-
Pediatric Asthma Score (lung, exam)
- Added
-
Pertussis (lung, Bacteria)
- Updates
-
Praziquantel (id, pharm)
- Added
-
Primaquine (id, pharm)
- Added
-
Procarbazine (hemeonc, pharm)
- Added
-
Pyrantel (id, pharm)
- Added
-
Pyrimethamine (id, pharm)
- Added
-
Quinine (id, pharm)
- Added
-
Streptozocin (hemeonc, pharm)
- Added
-
Tafenoquine (id, pharm)
- Added
-
Temozolomide (hemeonc, pharm)
- Added
-
Thiotepa (hemeonc, pharm)
- Added
-
Tibial Tuberosity Avulsion Fracture (ortho, knee)
- Added
-
Tinidazole (id, pharm)
- Added
-
Trabectedin (hemeonc, pharm)
- Added
-
Triclabendazole (id, Pharm)
- Added
-
Gepant (neuro, pharm)
- Updates
-
Tetanus (id, neuro)
- Updates
-
Toddler Fracture (ortho, ankle)
- Updates
-
Osteomyelitis (ortho, id)
- Updates
-
Cocoa (pharm, nutrition)
- Added
-
Brexanolone (psych, pharm)
- Added
-
Zuranolone (psych, pharm)
- Added
-
Hyperkalemia Management (renal, Potassium)
- Updates
-
Ring Removal (surgery, derm)
- Updates
-
Jehovah's Witness (Surgery, Manage)
- Added
-
Urinary Tract Infection (urology, Bladder)
- Updates
-
Unknown Ingestion (er, toxin)
- Extensive Updates
-
Varicella Zoster Virus (id, virus)
- Updates
IV. Updates: February 2024
-
Acute Coronary Syndrome (cv, cad)
- Updates
-
Hypotension Causes (cv, exam)
- Updates
-
Lice (derm, Parasite)
- Added and updated topical antiparasitic drugs
-
Scabies (derm, Parasite)
- Added and updated topical antiparasitic drugs
-
Topical Antifungal (derm, pharm)
- Created entries for each of the currently active agents, and updated their content
-
Obesity Management (endo, Obesity)
- Updates
- Basal Insulin (endo, pharm)
- Detemir is being discontinued
-
Snake Bite (er, derm)
- Updates
-
Scorpion Sting (er, derm)
- Updates
-
Hymenoptera Sting (er, derm)
- Updates
-
Vitreous Hemorrhage (eye, Retina)
- Updates
-
Retinal Detachment (eye, Retina)
- Updates
-
Optic Neuritis (eye, neuro)
- Updates
- Vanoprazan (gi, pharm)
- Added
-
Vomiting (gi, sx)
- Added pathway diagram
-
Progestin Only Pill (gyn, pharm)
- Norgestrel 75 mcg Oral Contraceptive will be OTC in 2024
-
Fibrinogen Concentrate (hemeonc, pharm)
- Added
-
Minimum Inhibitory Concentration (id, emerging)
- Added
-
Fluconazole (id, pharm)
- Extensive Updates
-
Flucytosine (id, pharm)
- Added
-
Griseofulvin (id, pharm)
- Extensive updates
-
Echinocandin (id, pharm)
- Added Caspofungin, Micafungin and Andulafungin
-
Ketoconazole (id, pharm)
- Extensive Updates
-
Isavuconazole (id, pharm)
- Added
-
Itraconazole (id, pharm)
- Extensive Updates
-
Posaconazole (id, pharm)
- Added
-
Terbinafine (id, pharm)
- Extensive Updates
-
Voriconazole (id, pharm)
- Added
-
Asthma Exacerbation (lung, Asthma)
- Updates
-
Mental Status Exam (neuro, exam)
- Updates
-
Phenytoin Toxicity (neuro, pharm)
- Updates
-
Prenatal Labs (ob, lab)
- Updates related to STI Screening and prevention
-
Acute Calcific Tendonitis of the Longus Colli (ortho, c-spine)
- Added. Thanks to Dr. Tony Genia, MD for sharing a case of ACTLC with me
- On the differential for Globus Hystericus and Dysphagia
-
Nursemaid's Elbow (ortho, elbow)
- Updates
-
Hip Injection (ortho, procedure)
- Updates
-
Knee Injection (ortho, procedure)
- Updates
-
Coenzyme Q10 (pharm, Vitamin)
- Updates
-
Alcohol Use Disorder Management (psych, cd)
- Updates including medications
-
Aripiprazole (psych, pharm)
- Updated long acting agents
-
Paliperidone (psych, pharm)
- Updated long acting agents
-
Risperidone (psych, pharm)
- Updated long acting agents
-
Metabolic Acidosis (renal, acidbase)
- Updates
-
Multisystem Inflammatory Syndrome (cv, peds)
- Updates
-
Infantile Hemangioma (derm, peds)
- Updates
-
Type 2 Diabetes Mellitus in Children (endo, dm)
- Updates
-
Pediatric Obesity (endo, peds)
- Updates
-
Tonsillectomy (ent, mouth)
- Updates
-
Bleeding Disorder (hemeonc, coags)
- Updates
-
Henoch-Schonlein Purpura (hemeonc, derm)
- Updates
-
Penicillin Allergy (id, pharm)
- Updates
-
Congenital Cytomegalovirus (id, virus)
- Updates
-
Sarcoidosis (lung, ILD)
- Updates
-
ADHD Medication (peds, neuro)
- Updates
-
Autism Spectrum Disorder (peds, neuro)
- Updates
-
Child Abuse (prevent, abuse)
- Updates
-
Obsessive Compulsive Disorder (psych, anxiety)
- Updates
-
Avoidant-Restrictive Food Intake Disorder (psych, eating)
- Updates
-
Adolescent Drug Abuse (psych, cd)
- Updates
-
Respiratory Syncytial Virus (lung, peds)
- Updates
-
Systemic Lupus Erythematosus (rheum, diffuse)
- Updates
-
Hypospadias (urology, peds)
- Updates
-
Neonatal Circumcision (urology, procedure)
- Updates
V. Updates: January 2024
-
Congestive Heart Failure Exacerbation Management (cv, chf)
- Acetazolamide speeds acute pulmonary decongestion in CHF exacerbation when added to Loop Diuretics
-
Cardiovascular Disease in Women (cv, gyn)
- Updates
-
Hypertension Management (cv, htn)
- At least one study shows no significant cardiovascular benefit to nighttime dosing over am dosing
-
Severe Asymptomatic Hypertension (cv, htn)
- Updates
-
Chlorthalidone (cv, pharm)
- Hydrochlorothiazide has similar cardiovascular outcomes and less risk of Hypokalemia
-
Statin-Induced Myalgias (cv, pharm)
- More than 90% of myalgias in patients taking Statins are NOT due to other cause or Nocebo Effect (see above)
-
Orbital Cellulitis (derm, eye)
- Updates to Preseptal Cellulitis and Orbital Cellulitis
-
Psoriasis (derm, hyperplasia)
- Extensive updates
-
SGLT2 Inhibitor Associated Ketosis (endo, dm)
- Updates
-
Ear Irrigation (ent, procedure)
- Updates
-
Chronic Hepatitis B Infection (gi, liver)
- Added and updated all nRTI agents used in Chronic HBV (Tenofovir, Entecavir, Adefovir, Lamivudine)
-
Pediatric Reflux (gi, peds)
- Updated regarding acid suppression precautions
-
Methylnaltrexone (gi, pharm)
- Updates
-
Adnexal Mass (gyn, hemeonc)
- Updates
-
Andexxa (hemeonc, pharm)
- Updates
-
Tenecteplase (hemeonc, pharm)
- Updates related to Intracerebral Hemorrhage risk
-
Anti-Retroviral Therapy (hiv, pharm)
- Updates
- Enfuviritide (hiv, pharm)
- Updates
-
Ibalizumab (hiv, pharm)
- Updates
-
Integrase Strand Transfer Inhibitor (hiv, pharm)
- Created entries for each of the currently active agents, and updated their content
-
Maraviroc (hiv, pharm)
- Updates
-
Nucleoside Reverse Transcriptase Inhibitor (hiv, pharm)
- Created entries for each of the currently active agents, and updated their content
-
Non-Nucleoside Reverse Transcriptase Inhibitor (hiv, pharm)
- Created entries for each of the currently active agents, and updated their content
-
Amphotericin B (id, pharm)
- Updates
-
Atovaquone (id, pharm)
- Updates
-
Clotrimazole (id, pharm)
- Updates
-
Miconazole (id, pharm)
- Updates
-
Nystatin (id, pharm)
- Updates
-
Pentamidine (id, pharm)
- Updates
-
COPD Management (lung, copd)
- Extensive updates based on GOLD 2023
-
Covid19 (lung, id)
- Added Angioedema as a manifestation
-
Dapsone (lung, pharm)
- Updates
-
Hemoptysis (lung, sx, bleed)
- Updates
-
Dementia Diagnosis (neuro, cognitive)
- Updates regarding Mental Status Exam tools
-
Neonatal Seizure (neuro, nicu, Seizure)
- Updates
-
Preconception Counseling (ob, prevent)
- Updates to Preconception Counseling and Pregnancy Risk Assessment, as well as Teratogen Exposure
-
Knee Dislocation (ortho, knee)
- Updates
-
Chronic Low Back Pain Management (ortho, L-Spine)
- Spinal stimulators appear to offer little benefit at 6 and 12 months (cochrane review)
-
St. Johns Wort (pharm, alternative)
- Updates
-
Omega-3 Fatty Acid Supplement (pharm, nutrition)
- Longterm Marine Omega 3 Fatty Acids (esp. >1 g/day) are associated with an increased risk of Atrial Fibrillation
-
Vitamin A Toxicity (pharm, Vitamins)
- Added
-
GRADE Approach (prevent, epi)
- Added
-
Hazard Ratio (prevent, epi)
- Added
-
Cannabinoid (psych, cd)
- Updates including longterm, continuous use adverse effects
-
Vaping-Associated Lung Disease (psych, cd)
- Updates
-
Renal Infarction (renal, cv)
- Added
- Chronic Kidney Disease (renal, failure)
-
Baking Soda (renal, pharm)
- Added to Oral Sodium Bicarbonate and the toxicity risk
-
Colchicine Toxicity (rheum, pharm)
- Added
- Exercise (sports, Exercise)
-
Pediatric Sports Overuse Injury (sports, peds)
- Added, and updated specific conditions
-
High Pressure Injection Wound (surgery, derm)
- Updates
-
Etomidate (surgery, pharm)
- May be associated with higher mortality when used for RSI based on metaanalysis
-
Urethral Catheterization (urology, procedure)
- Updates and pearls