II. Epidemiology
III. Management: Patient and Wound Site
- Consult Trauma surgery
- Early Hemorrhage Control is critical
- See Hemorrhage Management
- See Massive Blood Transfusion
- Primary focus after airway stabilization (if needed), and Hypoxia management
-
ABC Management
- Caution with Endotracheal Intubation in Hypovolemia (risk of cardiovascular collapse)
- High initial sympathetic drive and Vasoconstriction dissipates with Rapid Sequence Intubation
- Delay definitive airway management if possible until adequate hemodynamic stability
- Have push-dose pressors available for post-intubation Hypotension
- Caution with Endotracheal Intubation in Hypovolemia (risk of cardiovascular collapse)
-
Trauma Evaluation
- Evaluate for multisystem Trauma
- Prophylactic intravenous Antibiotics in significant amputations (proximal to digits)
- Initiate within 1 hour of hospital arrival to reduce risk of deep space infections
- First Generation Cephalosporins of Clindamycin
- Add Gram Negative coverage for more significant, multisystem injuries
- Add anaerobic coverage (e.g. Metronidazole, Clindamycin) for highly contaminated wounds, vascular injury
- Appelbaum (2024) Trauma Surg Acute Care Open 9(1):e001304 +PMID: 38835634 [PubMed]
- Other medications
- Analgesics (e.g. Ketamine, Fentanyl if hemodynamic instability)
- Intraveous fluids
- Tetanus Prophylaxis
- Irrigate wound site with copious amounts of sterile saline (or if unavailable, clean tap water)
- Local infections complicate >50% of life threatening extremity wounds requiring Tourniquet placement
- Rittblat (2024) Acad Emerg Med +PMID: 39686666 [PubMed]
- If amputated limb is still partially attached
- Avoid unnecessary manipulation
- Realign limb if rotated
- Splint in place
- Non-life threatening wounds (e.g. digits)
-
Wound Dressing
- Wrap wound in nonadherent Vaseline Gauze
- Apply dry compression bandage over Vaseline Gauze
- Keep wound cool with insulated cold water packs
IV. Management: Amputated Part Care
- Assign staff to be responsible for amputated part
- Gently clean limb
- Remove external debris
- Irrigate wound surface with sterile Isotonic Saline
- Do not submerge amputated part in liquid
- Wrap part in nonadherent Vaseline Gauze
- Dampen gauze with sterile Isotonic Saline
- Place amputated limb in closed sterile container
- Place container in ice water
- Do not discard any tissue until surgeon consulted
V. Management: Threatened Limb Evaluation and Reimplantation
- Consult reimplant surgeons
- Transfer to facility for possible limb reattachment
- Warm ischemia window of repair: 4-6 hours
- Evaluate limb viability (is limb salvageable)
- Tissue integrity
- Limb perfusion (pulses or handheld doppler)
- Neurologic function (motor and sensory)
- Hard signs of limb vascular injury (urgent surgical intervention)
- Absent distal pulses (and loss of doppler pulses)
- Expanding Hematoma
- Palpable thrill
- Audible bruit
- Pulsatile bleeding
- Indications for Reattachment of hand, wrist or Forearm
- Amputated limb or finger in children
- Multiple fingers involved
- Amputated thumb
- Clean amputation
- Risk factors for failed limb or digit reattachment
- Amputation through proximal phalanx (esp. index, pinky)
- Tobacco Abuse (61% versus 97% for non-smokers)
- Crush wound (68% versus 91% for clean-cut wound)
- Significantly contaminated wound
- Thumb (68%) or index finger (75%) versus third-fourth fingers (83%) or fifth finger (89%)
- Dec (2006) Tech Hand Up Extrem Surg 10(3): 124-9 [PubMed]
VI. Prognosis
- Unilateral lower Limb Amputation is associated with significant morbidity
- Longterm reduced mobility and independence
- High risk for medical and psychiatric complications
VII. References
- Antosia in Marx (2002) Rosens Emergency Med, p. 493-534
- Hori (2015) Crit Dec Emerg Med 29(3): 2-7
- Nutter (2026) Crit Dec Emerg Med 40(1): 22-3
- Daniels (2004) Am Fam Physician 69:1949-56 [PubMed]