II. Risk Factors
- Pre-existing Neuropathy (e.g. Diabetic Neuropathy)
-
Chemotherapy
- Vinca alkyloids
- Taxanes
- Platinum Antineoplastic Compound
- Bortezomib
III. Presentations
- Acute
- Onset with drug infusion
- Chronic
- Onset within days to weeks, or even months, after Chemotherapy
IV. Diagnostics
- History and exam is typically sufficient for diagnosis (EEG is not typically needed)
V. Management
- Exercise
- Acupuncture
- Medications
- Duloxetine
- Gabapentin and Pregabalin have been used (evidence lacking)
VI. Prevention
- Exercise
- Compression therapy
- Cryotherapy
- Ganglioside-monosialic acid