Emergency Medicine Book

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Accidental Poisoning Causes

Aka: Accidental Poisoning Causes, Poisoning Causes, Poisoning Causes in Children, Medication Overdose Causes
  1. See Also
    1. Poisoning
  2. Epidemiology: Incidence of specific agents in childhood Poisonings
    1. Most common: Cosmetics, personal care products, cleaning agents
    2. Moderately common: Analgesics, topicals, Cold Preparations
    3. Other: Plants, Pesticides, vitamins, Antihistamines, antibiotics, arts and craft supplies
    4. Watson (2005) Am J Emerg Med 23(5): 589-666
  3. Causes: Lethal agents to small children (<10 kg) in small doses (e.g. 1-2 tablets)
    1. Benzocaine
    2. Beta Blockers
    3. Calcium Channel Blockers
    4. Chloroquine
    5. Clonidine
    6. Iron preparations
      1. One of the most toxic agents in overdose for small children
      2. Morris (2000) South Med J 93(4): 352-8
    7. Lindane
    8. Lomotil
    9. Methadone
    10. Methyl Salicylate (oil of wintergreen - even in small amounts)
    11. Oxycodone
    12. Phenothiazines
    13. Phenylpropanolamine
    14. Podophyllum
    15. Quinine
    16. Quinidine
    17. Sulfonylureas
    18. Tea Tree Oil
    19. Theophylline
    20. Tricyclic Antidepressants
    21. Bar-Oz (2004) Paediatr Drugs 6(2): 123-6
  4. Causes: Medications with Higher Toxicity
    1. Beta Blockers
    2. Calcium Channel Blockers
    3. Chloroquine
    4. Clonidine
    5. Glucophage
    6. Iron preparations
    7. Isoniazid
    8. Lomotil
    9. Methadone
    10. Oxycodone
    11. Phenothiazines
    12. Phenylpropanolamine
    13. Quinine
    14. Quinidine
    15. Sulfonylureas
    16. Theophylline
    17. Tricyclic Antidepressants
  5. Causes: Non-Medications or Topical Agents with Higher Toxicity
    1. Alcohols (Ethanol, methanol, Ethylene Glycol)
    2. Benzocaine
    3. Caustics (e.g. toilet cleaners, drain cleaners)
    4. Hydrocarbons (Kerosene, furniture polish, paint thinner, lighter fluid)
    5. Lindane
    6. Methyl Salicylate (oil of wintergreen)
    7. Nail products (acetonitrile, methacrylic acid, nitromethane)
    8. Organophosphates
    9. Paraquat
    10. Podophyllum
    11. Tea Tree Oil
  6. Causes: Toxins with delayed effects in overdose
    1. Acetaminophen
    2. Acetonitrile
    3. Anticoagulants (e.g. Warfarin)
    4. Aspirin
    5. Carbamazepine (Tegretol)
    6. Dapsone
    7. Enteric-coated or sustained release medications
    8. Ethylene Glycol
    9. Iron
    10. Lithium
    11. Lomotil
    12. Meprobamate
    13. Methanol
    14. Monoamine Oxidase Inhibitors
    15. Sulfonylureas
    16. Theophylline
    17. Thyroid hormones
    18. Toxic Mushrooms
    19. Barry (2005) Pediatr Ann 34(12):937-46

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