Give 2 mg IV or IM every 3-5 minutes to a total of 10-20 mg
Naloxone 2 mg in 500 ml D5W or NS (0.004 mg/ml) titrating to response
No respiratory depression: 0.01 mg/kg IV or IM
Respiratory depression: 0.1 mg/kg IV or IM
Next, if no response or incomplete response
Give 0.1 mg/kg IV or IM
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FPnotebook.com is a rapid access, point-of-care medical reference for primary care and emergency clinicians. Started in 1995, this collection now contains 6331 interlinked topic pages divided into a tree of 31 specialty books and 719 chapters. Content is updated monthly with systematic literature reviews and conferences.
Although access to this website is not restricted, the information found here is intended for use by medical providers. Patients should address specific medical concerns with their physicians.
This page was written by Scott Moses, MD, last revised on 10/3/2014 and last published on 3/20/2015.