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Miosis
Aka: Miosis, Pupil constriction, Consensual Light Reaction, Near Reaction
- Pupil constriction as a normal response
- Parasympathetic stimulation
- Near Reaction (e.g. Reading)
- Pupil constriction mediated by Oculomotor Nerve
- Other changes with Near Reaction
- Eye convergence under Oculomotor Nerve control
- Accomodation (Lenses become more convex)
- Bright light results in bilateral Pupil constriction
- Direct reaction to light in exposed eye
- Light strikes Retina of affected eye
- Signal passed via Optic Nerve to Midbrain
- Oculomotor Nerve signals same iris to constrict
- Consensual Light Reaction in opposite eye
- Midbrain receives signal from exposed eye
- Oculomotor Nerve sinals opposite iris to constrict
- Abnormal Causes
- Mnemonic: COPS
- Cholinergic Toxicity
- Clonidine
- Opiate Overdose
- Responds to Naloxone (except synthetic opiates)
- Organophosphate Toxicity
- Phenothiazines
- Pilocarpine
- Pontine bleed or lesion
- Sedative hypnotics (Benzodiazepine)
- Horner's Syndrome