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Horner's Syndrome

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  1. Pathophysiology
    1. Paralysis of superior cervical Sympathetic Nerve
      1. Destructive lesion to superior cervical ganglion
      2. Destruction in posterior retroparotid space
      3. Mediastinal tumor
    2. Associated lesions
      1. Cranial Nerve 9
      2. Cranial Nerve 10
      3. Cranial Nerve 11
      4. Cranial Nerve 12
  2. Causes
    1. Brainstem stroke
    2. Posterior retroparotid space mass
      1. Parotid Gland tumor
      2. Carotid body tumor
      3. Metastatic tumor
      4. Lymphoma
      5. Tuberculous Adenitis
    3. Mediastinal mass
  3. Signs
    1. Mnemonic: Miosis, Ptosis, Anhydrosis
    2. All findings are unilateral
    3. Miosis
    4. Palpebral Ptosis (Incomplete)
      1. Contrast with complete Ptosis in levator paralysis
      2. Illusion of eyeball recession (No true enophthalmos)
    5. Absence of sweating (Anhydrosis) on face and neck

Ocular-Ophthalmoplegia, Sympathetic (C0019937)

Definition (MSH)A syndrome associated with defective sympathetic innervation to one side of the face, including the eye. Clinical features include MIOSIS; mild BLEPHAROPTOSIS; and hemifacial ANHIDROSIS (decreased sweating)(see HYPOHIDROSIS). Lesions of the BRAIN STEM; cervical SPINAL CORD; first thoracic nerve root; apex of the LUNG; CAROTID ARTERY; CAVERNOUS SINUS; and apex of the ORBIT may cause this condition. (From Miller et al., Clinical Neuro-Ophthalmology, 4th ed, pp500-11)
Definition (CSP)syndrome associated with defective sympathetic innervation to one side of the face, including the eye; clinical features include miosis, mild blepharoptosis, and hemifacial anhidrosis (decreased sweating); lesions of the brain stem, cervical spinal cord, first thoracic nerve root, apex of the lung, carotid artery, cavernous sinus, and apex of the orbit may cause this condition.
Definition (NCI)A condition in which one side of the face is flushed, does not produce sweat, and has a constricted pupil and drooping eyelid. It can be caused by an injury to, or paralysis of, nerves in the neck, or by a tumor.
ConceptsDisease or Syndrome (T047)
EnglishBernard Horner syndrome, Bernard Syndrome, Bernard Syndromes, Bernard's Syndrome, Bernards Syndrome, Cervical sympathetic paralysis, CERVICAL SYMPATHETIC PARALYSIS SYNDROME, Claude Bernard Horner Syndrome, Claude Bernard-Horner Syndrome, Horner Syndrome, Horner's Syndrome, Horners Syndrome, Oculosympathetic Syndrome, Oculosympathetic Syndromes, Sympathetic Ocular Ophthalmoplegia, Sympathetic Ocular Ophthalmoplegias, Sympathetic Ocular-Ophthalmoplegia, Sympathetic Ocular-Ophthalmoplegias
Spanishmielopatia por paralisis de nervios simpaticos, paralisis simpatica cervical, sindrome de Horner
Parent ConceptsEye diseases (C0015397), Syndrome (C0039082), Autonomic nervous system disorders (C1145628), Miosis disorder (C0026205), Neuropathy (C0442874), Idiopathic peripheral autonomic neuropathy NOS (C0154690), Nervous System Diseases, Sympathetic (C0750946), Ambiguous concept (C1274012)
SourcesCOSTAR, CSP, DXP, MSH, MTH, NCI, NDFRT, OMIM, QMR, SCTSPA, SNOMEDCT
Derived from the NIH UMLS (Unified Medical Language System)



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