II. Indications: Atrial Fibrillation Cardioversion

  1. Time to Cardioversion: 3-8h
  2. Conversion Rate: 51-76%
  3. Chronic Efficacy: 50-60%

III. Dose: Adults

  1. Load: 600 mg PO single bolus dose
  2. Maintenance: 150-300 mg PO tid

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Cost: Medications

propafenone (on 8/17/2016 at Medicaid.Gov Survey of pharmacy drug pricing)
PROPAFENONE HCL 150 MG TABLET Generic $0.18 each
PROPAFENONE HCL 225 MG TAB Generic $0.28 each
PROPAFENONE HCL 300 MG TAB Generic $0.87 each
PROPAFENONE HCL ER 225 MG CAP Generic $5.11 each
PROPAFENONE HCL ER 325 MG CAP Generic $6.56 each
PROPAFENONE HCL ER 425 MG CAP Generic $6.95 each
rythmol (on 1/1/2016 at Medicaid.Gov Survey of pharmacy drug pricing)
RYTHMOL SR 225 MG CAPSULE Generic $5.11 each
RYTHMOL SR 325 MG CAPSULE Generic $6.56 each

Ontology: Propafenone (C0033429)

Definition (MSH) An antiarrhythmia agent that is particularly effective in ventricular arrhythmias. It also has weak beta-blocking activity.
Concepts Pharmacologic Substance (T121) , Organic Chemical (T109)
MSH D011405
SnomedCT 372910007, 96300001
LNC LP17241-8, MTHU012323
English Propafenone, 1-Propanone, 1-(2-(2-hydroxy-3-(propylamino)propoxy)phenyl)-3-phenyl-, Propafenone [Chemical/Ingredient], PROPAFENONE, propafenone, Propafenone (product), Propafenone (substance)
Swedish Propafenon
Czech propafenon
Finnish Propafenoni
Russian PROPAFENON, ПРОПАФЕНОН
Japanese プロパフェノン
Polish Propafenon
Spanish propafenona (producto), propafenona (sustancia), propafenona, Propafenona
French Propafénone
German Propafenon
Italian Propafenone
Portuguese Propafenona

Ontology: Rythmol (C0282316)

Concepts Pharmacologic Substance (T121) , Organic Chemical (T109)
MSH D011405
English Rytmonorm, rythmol, Arythmol, Rythmol, Knoll Brand of Propafenone Hydrochloride, Norfenon, Pintoform, Propafenon Minden, Abbott Brand of Propafenone Hydrochloride