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Metoprolol

Aka: Metoprolol, Lopressor
  1. See Also
    1. Beta Blocker
  2. Mechanism
    1. Selective Beta Blocker
  3. Indications
    1. Myocardial Infarction
    2. Atrial Fibrillation Rate Control
  4. Pharmacokinetics
    1. Onset of action in 5 minutes after intravenous dose
    2. Sustained response for 6-8 hours
  5. Dosing: Oral
    1. Regular: 50 mg PO bid (Maximum 450 mg/day)
    2. Extended: 50-100 mg PO qd (Maximum 400 mg/day)
  6. Dosing: Intravenous
    1. Load: 2.5 to 5 mg IV over 2 to 5 minutes
    2. Repeated up to 3 doses (15 mg maximum)

Lopressor (C0700776)

Concepts Organic Chemical (T109) , Pharmacologic Substance (T121)
MSH D008790
English Lopresor, Novartis Brand of Metprolol Tartrate, lopresor, lopressor, Lopressor
Sources
Derived from the NIH UMLS (Unified Medical Language System)


Metoprolol (C0025859)

Definition (MSH) A selective adrenergic beta-1 blocking agent that is commonly used to treat ANGINA PECTORIS; HYPERTENSION; and CARDIAC ARRHYTHMIAS.
Definition (NCI) A cardioselective competitive beta-1 adrenergic receptor antagonist with antihypertensive properties and devoid of intrinsic sympathomimetic activity. Metoprolol antagonizes beta 1-adrenergic receptors in the myocardium, thereby reducing the rate and force of myocardial contraction leading to a reduction in cardiac output. This agent may also reduce the secretion of renin with subsequent reduction in levels of angiotensin II thereby preventing vasoconstriction and aldosterone secretion.
Concepts Organic Chemical (T109) , Pharmacologic Substance (T121)
MSH D008790
SnomedCT 372826007, 7092007
English Metoprolol, 2-Propanol, 1-(4-(2-methoxyethyl)phenoxy)-3-((1-methylethyl)amino)-, (+-)-, metoprolol, metoprolol (medication), Metoprolol [Chemical/Ingredient], Metoprolol (product), Metoprolol (substance), METOPROLOL
Swedish Metoprolol
Czech metoprolol
Finnish Metoprololi
Russian N 93-26, METOPROLOL, МЕТОПРОЛОЛ, Н 93-26
Japanese 酒石酸メトプロロール, セレクナート, メデピン, メルコモン, ロプレソール, セロケン, ロプレソールSR, シオプトロール, セグミューラー, ココナリン, シプセロン, モジュメニー, セロケンL, メトプリック, メトラスター, カルスホン, メトプロロール
Polish Metoprolol
Spanish metoprolol (producto), metoprolol (sustancia), metoprolol, Metoprolol
French Métoprolol
German Metoprolol
Italian Metoprololo
Portuguese Metoprolol
Sources
Derived from the NIH UMLS (Unified Medical Language System)


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