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Flecainide
Aka: Flecainide, Tambocor- Indications: Atrial Fibrillation Cardioversion
- Time to Cardioversion: 3-8 hours
- Conversion Rate: 68-91%
- Chronic Efficacy: 40-74%
- Dose
- Load: 300-400 mg PO single bolus dose
- Maintenance: 50-150 mg PO bid
Flecainide (C0016229) |
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|---|---|
| Definition (MSH) | A potent anti-arrhythmia agent, effective in a wide range of ventricular and atrial arrhythmias and tachycardias. Paradoxically, however, in myocardial infarct patients with either symptomatic or asymptomatic arrhythmia, flecainide exacerbates the arrhythmia and is not recommended for use in these patients. |
| Definition (NCI) | A drug that is used to treat abnormal heart rhythms. It may also relieve neuropathic pain, the burning, stabbing, or stinging pain that may arise from damage to nerves caused by some types of cancer or cancer treatment. |
| Definition (NCI) | A synthetic agent derived from trifluoroethoxy-benzamide exhibiting antiarrhythmic and local anesthetic activity. As a class Ic antiarrhythmic that blocks sodium channels, flecainide depresses polarization phase 0 and decreases the induction velocity of the His-Purkinje system. It also decreases phase 4 slope and increases the depolarization threshold. (NCI04) |
| Concepts | Organic Chemical (T109) , Pharmacologic Substance (T121) |
| MSH | D005424 |
| SnomedCT | 372751001, 46576005 |
| English | Flecainide, Benzamide, N-(2-piperidinylmethyl)-2,5-bis(2,2,2-trifluoroethoxy)-, flecainide, flecainide (medication), Flecainide [Chemical/Ingredient], Flecainide (product), Flecainide (substance), FLECAINIDE |
| Swedish | Flekainid |
| Czech | flekainid |
| Finnish | Flekainidi |
| Russian | FLEKAINIDA ATSETAT, FLEKAINID, ФЛЕКАИНИД, ФЛЕКАИНИДА АЦЕТАТ |
| Polish | Flekainid |
| Japanese | 酢酸フレカイニド, フレカイニド |
| Spanish | flecainida (producto), flecainida (sustancia), flecainida, Flecainida |
| French | Flécaïnide |
| German | Flecainid |
| Italian | Flecainide |
| Portuguese | Flecainida |
| Sources |
Derived from the NIH UMLS (Unified Medical Language System) |
Tambocor (C0592158) |
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|---|---|
| Concepts | Organic Chemical (T109) , Pharmacologic Substance (T121) |
| MSH | D005424 |
| English | tambocor, Tambocor, Apocard, Flécaïne, Riker Brand of Flecainide Acetate, United Drug Brand of Flecainide Acetate, 3M Brand of Flecainide Acetate |
| Sources |
Derived from the NIH UMLS (Unified Medical Language System) |