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PropranololAka: Inderal
- Mechanism
- Non-Selective Beta Blocker
- Indications
- Hypertension
- Atrial Fibrillation Rate Control
- Hyperthyroidism
- Performance Anxiety
- Dosing: Oral
- Regular: 40 mg PO bid (MAX: 640 mg/day)
- Extended: 80 mg PO qd (MAX: 320 mg/day)
- Dosing: Intravenous
- Load: 1-3 mg IV over 2-5 minutes
- Repeat every 2 minutes to a total dose of 0.1 mg/kg
- Sustained response for 6-8 hours
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| Definition (MSH) | A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs. |
| Definition (CSP) | noncardioselective beta adrenergic antagonist; used in treatment or prevention of many disorders including acute myocardial infarction, arrhythmias, angina pectoris, hypertension, hyperthyroidism, migraine; pheochromocytoma, etc. |
| Definition (NCI) | A synthetic, nonselective beta-adrenergic receptor blocker with antianginal, antiarrhythmic, antihypertensive properties. Propranolol competitively antagonizes beta-adrenergic receptors, thereby causing negative chronotropic and inotropic effects leading to a reduction in cardiac output. |
| Concepts | Organic Chemical (T109)
, Pharmacologic Substance (T121)
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| English | Propanolol, Propranolol, PROPRANOLOL PREPARATION |
| Spanish | propranolol |
| Credits | Derived from the NIH UMLS (Unified Medical Language System)
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