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HallucinogenAka: Lysergic Acid, LSD, Mescaline, Psilocybin

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  1. See Also
    1. Chemical Dependency
    2. Substance Abuse Evaluation
  2. Background
    1. Derivations
      1. LSD semisynthetically derived from ergot alkaloids
      2. Mescaline naturally derived from peyote
      3. Psilocybin naturally derived from Psilocybe
    2. Pharmacokinetics
      1. LSD (50-400 ug): 8-12 hour duration
      2. Mescaline (250-600 mg): 8-12 hour duration
      3. Psilocybin (10-50 mg): 6-8 hour duration
  3. Forms or Street Names
    1. Lysergic Acid Diethylamide (LSD)
      1. Acid
      2. Sugar
      3. Cubes
      4. Trips
      5. Windowpane
      6. Blotter
    2. Mescaline
      1. Buttons
      2. Beans
      3. Cactus
    3. Psilocybin
      1. Magic Mushrooms
      2. Mushroom
      3. Los ninos
  4. Signs
    1. Hyper-suggestible state
  5. Toxicity: Amphetamine-like reaction
    1. Hyperthermia
    2. Rhabdomyolysis
    3. Severe Hyponatremia
    4. Cerebral Infarction
  6. Toxicity Management
    1. Provide calm and supportive environment

Lysergic Acid Diethylamide (C0024334)

Definition (MSH)Semisynthetic derivative of ergot (Claviceps purpurea). It has complex effects on serotonergic systems including antagonism at some peripheral serotonin receptors, both agonist and antagonist actions at central nervous system serotonin receptors, and possibly effects on serotonin turnover. It is a potent hallucinogen, but the mechanisms of that effect are not well understood.
Definition (CSP)semisynthetic derivative of ergot; it has complex effects on serotonergic systems including antagonism at some peripheral serotonin receptors, both agonist and antagonist actions at central nervous system serotonin receptors, and possibly effects on serotonin turnover; it is a potent hallucinogen and psychotomimetic.
ConceptsOrganic Chemical (T109) , Pharmacologic Substance (T121) , Hazardous or Poisonous Substance (T131)
EnglishLSD, LSD 25, Lysergate diethylamide, Lysergic Acid Diethylamide, Lysergide
Spanishácido lisérgico, acido lisergico, dietilamida de ácido lisérgico, dietilamida de acido lisergico, lisergida, LSD
CreditsDerived from the NIH UMLS (Unified Medical Language System)


Mescaline (C0025460)

Definition (MSH)Hallucinogenic alkaloid isolated from the flowering heads (peyote) of Lophophora (formerly Anhalonium) williamsii, a Mexican cactus used in Indian religious rites and as an experimental psychotomimetic. Among its cellular effects are agonist actions at some types of serotonin receptors. It has no accepted therapeutic uses although it is legal for religious use by members of the Native American Church.
ConceptsOrganic Chemical (T109) , Hazardous or Poisonous Substance (T131)
EnglishMescalin, Mescalin substance of abuse, Mescaline, mescaline in any form, Peyote extract, Trimethoxyphenethylamine
Spanishextracto de peyote, mescalina
CreditsDerived from the NIH UMLS (Unified Medical Language System)



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