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PhencyclidineAka: PCP
- See Also
- Class
- Hallucinogen
- Schedule II
- Street Names
- Angel dust
- Hog
- Horse Tranquilizer
- Pharmacokinetics
- PCP (2-10 mg): 3-18 hour duration
- Toxicity
- General Toxicity
- Severe Overdose
- Coma
- Seizure
- Hypotension or Hypertension
- Muscular rigidity to severe Hypothermia
- Rhabdomyolysis
- Toxicity Management
- Consider Restraints for Violent Behavior
- Benzodiazepines
- External cooling
- Dantrolene (Muscle Relaxant) Indications
- Severe hyperthermia
- Rhabdomyolysis
Phencyclidine (C0031381) | |
|---|---|
| Definition (MSH) | A hallucinogen formerly used as a veterinary anesthetic, and briefly as a general anesthetic for humans. Phencyclidine is similar to KETAMINE in structure and in many of its effects. Like ketamine, it can produce a dissociative state. It exerts its pharmacological action through inhibition of NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE). As a drug of abuse, it is known as PCP and Angel Dust. |
| Definition (CSP) | this drug is both a legitimate prescription anesthetic and a notoriously abused street drug also known as "angel dust." |
| Definition (NCI) | Phencyclidine (PCP) was developed as an anesthetic for humans in 1959. Its use was discontinued due to extreme side effects that included delirium, confusion, visual disturbances, hallucinations and violence. Some evidence of long-term memory disorders and schizophrenia-like syndrome have been observed. It is a substance of abuse, combining effects produced by depressants, stimulants, and hallucinogens. Can cause physical and psychological distress, coma, seizures and convulsions, respiratory depression, and cardiac problems. In addition, phencyclidine is a notorious street drug known as "angel dust."(NCI) |
| Concepts | Organic Chemical (T109) , Pharmacologic Substance (T121) |
| MSH | D010622 |
| English | Angel Dust, PCP, PCP - Phencyclidine, Phencyclidine, Phencyclidine substance of abuse |
| Spanish | fenciclidina, polvo de angel |
| Parent Concepts | hallucinogens of abuse (C0687138), Anesthetics (C0002932), Hallucinogens (C0018533), piperidine (C0031959), Piperidines (C0031960), Substance of abuse (C0687130), Hallucinogen - non-pharmaceutical (C0556620), Duplicate concept (C1274013) |
| Sources | AOD, CSP, LCH, LNC, MSH, MTH, NCI, SCTSPA, SNOMEDCT Derived from the NIH UMLS (Unified Medical Language System) |
