II. Preparations

  1. Medical and endogenous
    1. Alpha Adrenergic Agonists (also have beta effects as well)
      1. Epinephrine
      2. Norepinephrine
    2. Beta Adrenergic Agonists
      1. Isoproterenol
      2. Dobutamine
      3. Albuterol
  2. Illicit and non-medical
    1. Cocaine
    2. Amphetamines (MDMA or Ecstasy, Methamphetamine)
    3. Synthetic Cathinones (Psychoactive Bath Salts)
    4. Ephedrine
    5. Nicotine
    6. Caffeine

III. Physiology: Receptor Types

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Ontology: Catecholamines (C0007412)

Definition (NCI_NCI-GLOSS) A type of neurohormone (a chemical that is made by nerve cells and used to send signals to other cells). Catecholamines are important in stress responses. High levels cause high blood pressure which can lead to headaches, sweating, pounding of the heart, pain in the chest, and anxiety. Examples of catecholamines include dopamine, epinephrine (adrenaline), and norepinephrine (noradrenaline).
Definition (NCI) A group of sympathetic amines containing a catechol group derived from the amino acid tyrosine. Catecholamines are hormones and neuromodulators synthesized in the chromaffin cells of the adrenal glands and the postganglionic fibers of the sympathetic nervous system in response to stress. Examples of catecholamines are epinephrine (adrenaline), norepinephrine (noradrenaline) and dopamine, all of which participate in a wide variety of functions throughout the body.
Definition (MSH) A general class of ortho-dihydroxyphenylalkylamines derived from tyrosine.
Definition (CSP) any of various substances that contain a benzene ring with two adjacent hydroxyl groups and a side chain of ethylamine and that function as hormones or neurotransmitters or both; examples are dopamine, norepinephrine, and epinephrine.
Concepts Neuroreactive Substance or Biogenic Amine (T124) , Pharmacologic Substance (T121)
MSH D002395
SnomedCT 34582008
LNC LP15090-1, MTHU003446
English Catecholamines, Sympathins, Coumel, Catecholamines [Chemical/Ingredient], catecholamines, sympathin, coumel, catecholamine, Catecholamine, Total catecholamines, Catecholamine (substance), Catecholamine, NOS
Swedish Katekolaminer
Czech katecholaminy
Finnish Katekoliamiinit
Italian Simpatine, Catecolamine
Russian SIMPATINY, KATEKHOLAMINY, КАТЕХОЛАМИНЫ, СИМПАТИНЫ
Japanese カテコールアミン, シンパチン, カテコラミン
Croatian KATEKOLAMINI
Polish Sympatyny, Katecholaminy, Aminy katecholowe
Norwegian Not Translated[Catecholamines]
Spanish catecolamina (sustancia), catecolamina, Catecolaminas, Simpatinas
French Catécholamines
German Catecholamine, Katecholamine, Sympathine
Portuguese Catecolaminas, Simpatinas

Ontology: Adrenergic Receptor (C0034783)

Definition (MSH) Cell-surface proteins that bind epinephrine and/or norepinephrine with high affinity and trigger intracellular changes. The two major classes of adrenergic receptors, alpha and beta, were originally discriminated based on their cellular actions but now are distinguished by their relative affinity for characteristic synthetic ligands. Adrenergic receptors may also be classified according to the subtypes of G-proteins with which they bind; this scheme does not respect the alpha-beta distinction.
Definition (PSY) Class of neural receptors that are sensitive to the neurotransmitters epinephrine and norepinephrine.
Definition (CSP) family of G protein coupled receptors sensitive to epinephrine, norepinephrine, and their analogs, found in smooth and cardiac muscle, autonomic ganglia, brain, and elsewhere.
Concepts Receptor (T192) , Amino Acid, Peptide, or Protein (T116)
MSH D011941
SnomedCT 59208001
English Adrenergic Receptor, Adrenergic Receptors, Adrenoceptors, Receptor, Adrenergic, Receptors, Adrenergic, Epinephrine Receptors, Receptors, Epinephrine, adrenergic receptor, RECEPT ADREN, RECEPT EPINEPHRINE, EPINEPHRINE RECEPT, ADREN RECEPT, Adrenergic receptor site, Receptors, Adrenergic [Chemical/Ingredient], adrenergic receptors, adrenoceptors, adrenergic receptor sites, adrenoceptor, Adrenaline--Receptors, Adrenergic receptor (substance), Adrenergic receptor, Adrenaline Receptors, Receptors (Adrenergic), adrenoreceptor
Swedish Receptorer, adrenerga
Finnish Adrenergiset reseptorit
Italian Adrenorecettori, Recettore adrenergico, Recettori dell'epinefrina, Recettori adrenergici
Russian ADRENERGICHESKIE RETSEPTORY, RETSEPTORY ADRENERGICHESKIE, ADRENORETSEPTORY, RETSEPTORY ADRENALINA, RETSEPTORY NOREPINEFRINA, RETSEPTORY EPINEFRINA, RETSEPTORY NORADRENALINA, АДРЕНЕРГИЧЕСКИЕ РЕЦЕПТОРЫ, АДРЕНОРЕЦЕПТОРЫ, РЕЦЕПТОРЫ АДРЕНАЛИНА, РЕЦЕПТОРЫ АДРЕНЕРГИЧЕСКИЕ, РЕЦЕПТОРЫ НОРАДРЕНАЛИНА, РЕЦЕПТОРЫ НОРЭПИНЕФРИНА, РЕЦЕПТОРЫ ЭПИНЕФРИНА
Japanese 受容体-アドレナリン作用性, 受容体-ノルエピネフリン, エピネフリン受容体, 交感神経受容体, 受容体-アドレナリン, ノルエピネフリン受容体, アドレナリン作用性受容体, アドレナリン受容体
Croatian RECEPTORI, ADRENERGIČKI
French Adrénorécepteurs, Récepteurs de l'adrénaline, Récepteurs de l'épinéphrine, Récepteurs à l'adrénaline, Récepteurs adrénergiques, Récepteurs à l'épinéphrine
Czech receptory epinefrinu, adrenergní receptory, receptory adrenergní, adrenoreceptory
Polish Receptory adrenergiczne
Spanish receptor adrenérgico (sustancia), receptor adrenérgico, Adrenorreceptores, Receptores de Epinefrina, Receptores Adrenérgicos
German Adrenerge Rezeptoren, Adrenorezeptoren, Rezeporen, Epinephrin-, Rezeptoren, adrenerge
Portuguese Adrenoceptores, Receptores Adrenérgicos, Receptores da Epinefrina

Ontology: Sympathomimetics (C0039052)

Definition (MSH) Drugs that mimic the effects of stimulating postganglionic adrenergic sympathetic nerves. Included here are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters.
Concepts Pharmacologic Substance (T121)
MSH D013566
SnomedCT 349942009, 86308005, 372884008
LNC LP18076-7, MTHU003355
English Agents, Sympathomimetic, Drugs, Sympathomimetic, Sympathomimetic Agents, Sympathomimetic Drugs, Sympathomimetic compound, sympathomimetic agent, sympathomimetics (medication), sympathomimetics, sympathomimetic drug, sympathomimetic drugs, sympathomimetic agents, sympathomimetic, Sympathomimetic compound (product), Sympathomimetic agents, Sympathomimetic, Sympathomimetic agent (product), Sympathomimetic agent (substance), Sympathomimetic agent, Sympathomimetics, Sympathomimetic agent, NOS, Sympathomimetic compound (substance)
French Médicaments sympathomimétiques, Agents sympathomimétiques, Sympathomimétiques
Swedish Sympatomimetika
Czech sympatomimetika
Finnish Sympatomimeetit
Italian Farmaci simpatomimetici, Sostanze simpatomimetiche, Simpatomimetici
Russian SIMPATOMIMETICHESKIE SREDSTVA, AMINY SIMPATOMIMETICHESKIE, АМИНЫ СИМПАТОМИМЕТИЧЕСКИЕ, СИМПАТОМИМЕТИЧЕСКИЕ СРЕДСТВА
Japanese 交感神経効果薬, 交感神経作動薬, 交感神経様作用薬, 交感神経興奮性アミン, 交感神経作用薬, 交感神経刺激薬, アミン-交感神経興奮性, 交感神経効果剤
Croatian SIMPATOMIMETICI
Polish Sympatomimetyki, Środki pobudzające układ współczulny, Leki sympatykomimetyczne
Spanish compuesto simpaticomimético (producto), compuesto simpaticomimético, Efecto Simpatomimético, agente simpaticomimético (producto), agente simpaticomimético (sustancia), agente simpaticomimético, simpaticomimético, Simpatomiméticos
Portuguese Efeito Simpatomimético, Simpatomiméticos
German Adrenerge Substanzen, Sympathomimetika