II. Medications: Avoid in G6PD Deficiency

  1. Anti-Malarials
    1. Primaquine
    2. Pamaquine
  2. Sulfonamides
    1. Sulfacetamide
    2. Sulfanilamide
    3. Sulfamethoxazole (e.g. Septra, Bactrim)
    4. Sulfasalazine
  3. Anti-Bacterials
    1. Nitrofurantoin
    2. Nalidixic Acid
    3. Dapsone
    4. Mafenide Cream (Sulfamylon)
  4. Analgesics
    1. Phenacetin
    2. Acetanilid
    3. Phenazopyridine (Pyridium)
  5. Miscellaneous
    1. Quinine
    2. Flutamide (Eulexin)
    3. Methylene Blue
    4. Rasburicase

III. Medications: Safe in G6PD

  1. General
    1. Drugs previously thought contraindicated in G6PD
    2. May not apply to Class I G6PD
  2. Analgesics
    1. Acetaminophen
    2. Aspirin
    3. Aurodex
  3. Cardiovascular Agents
    1. Procainamide
    2. Quinidine
  4. Neurologic Agents
    1. Trihexyphenidyl
    2. Levodopa
    3. Phenytoin
  5. Antibiotics
    1. Chloramphenicol
    2. Chloroquine
    3. Isoniazid
    4. Probenecid
    5. Proguanil
    6. Pyrimethamine
  6. Miscellaneous
    1. Vitamin C
    2. Colchicine
    3. Diphenhydramine

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