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Meniere's Disease
Aka: Meniere's Disease, Labyrinthine Hydrops, Endolymphatic Hydrops
- Etiology
- Unknown
- Exacerbated by stress or emotional disturbance
- Associated with concurrent infection in 50% cases
- Pathophysiology
- Swelling of endolymphatic labyrinthine spaces
- Degeneration of the Organ of Corti
- Symptoms
- Prodrome
- Headache
- Triad
- Tinnitus: "Roaring", low tone
- Vertigo: Recurrent episodic
- Sensorineural Hearing Loss: fluctuant
- Usually unilateral
- But 33% have bilateral disease
- Dizziness
- May last minutes to hours, days when severe
- Signs
- Nystagmus
- Only present when Vertigo present
- Sensorineural Hearing Loss
- Early: Low tones affected
- Later: All tones affected
- Management: Acute
- Diazepam IV
- Atropine IV
- Transdermal Scopolamine
- Management: Maintenance
- Medications
- Diazepam
- Bellergal
- Meclizine
- Low salt diet (<2 grams daily)
- Decrease caffeine
- Smoking Cessation
- Diuretics (Dyazide)
- Management: ENT
- Ablation of vestibular hair cells
- Performed with intratympanic injection of Gentamicin
- Surgery: (10% of patients with refractory cases)
- Decompress endolymphatic sacs (Symptom relief in 66%)
- Vestibular nerve section (Symptom relief in 95%)
- No procedure corrects the Hearing Loss
- References
- Glasscock (1984) Am J Otol 5:536-42
- Knox (1997) Am Fam Physician 55(4):1185-90