II. Epidemiology

  1. Most common type of Hypertension in adults

III. Criteria

  1. Systolic Blood Pressure: >140 mmHg (previously >160)
  2. Diastolic Blood Pressure: <90 mmHg

IV. Complications: Cardiovascular Risk

  1. General
    1. Systolic pressure predicts risk better than diastolic
    2. Wide Pulse Pressure best predicts Cardiovascular Risk
  2. Adverse Effects
    1. Doubles all cause mortality
    2. Triples cardiovascular mortality
    3. Increases cardiovascular morbidity 2.5 fold

V. Management

  1. Use lower Antihypertensive dosages
  2. Diuretics are first Choice Medication
    1. Even better benefit in Diabetes Mellitus with ISH
    2. Study of 4736 type II diabetics
      1. Lower Incidence of cardiac events
        1. Lower Incidence of Cerebrovascular Accidents
        2. Lower Incidence of Myocardial Infarction
      2. Reference
        1. Curb (1996) JAMA 276: 1886-92 [PubMed]
  3. Other Medications
    1. Dihydropyridine Calcium Channel Blocker
    2. Long Acting Nitroglycerin
    3. ACE Inhibitor
    4. Labetalol

Images: Related links to external sites (from Bing)

Related Studies