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Antihypertensive SelectionAka: Hypertension Monotherapy
- See Also
- Step 1: Determine when and how to intervene
- Review Hypertension Risk Stratification
- Determine Hypertension Reduction Goal
- Step 2
- Consider Hypertension Combination Therapy
- Monotherapy
- Standard initial monotherapy choices
- Diuretics (e.g. Hydrochlorothiazide)
- If Diuretic is not first, it should be second
- Excellent adjunct to other antihypertensives
- Better outcomes than Lisinopril and Amlodipine
- Reduced risk of CVA, MI, CHF over other agents
- (2002) JAMA 288:2981
- Beta Blocker
- ACE Inhibitor
- Angiotensin Receptor Blocker
- Diuretics (e.g. Hydrochlorothiazide)
- Compelling reason for other antihypertensive
- Agents to avoid for monotherapy
- Alpha blockers
- Hydralazine
- Minoxidil
- Calcium Channel Blockers
- Avoid if non-compliant (rebound Hypertension)
- Standard initial monotherapy choices
- Step 3
- Consider Hypertension Combination Therapy