Nephrology Book

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Familial Periodic ParalysisAka: Hypokalemic Periodic Paralysis

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  1. Epidemiology
    1. Onset of symptoms before 20 yo
  2. Pathophysiology
    1. Autosomal dominant disorder of Hypokalemia
  3. Symptoms
    1. Headaches
    2. Thirst
    3. Lethargy
  4. Signs
    1. Slow progressive weakness
    2. Intermittent muscular paralysis
      1. Shoulder
      2. Pelvic girdle
      3. Other areas follow
    3. Muscle strength normal between attacks
    4. Deep Tendon Reflexes
      1. Diminished or absent
  5. Labs
    1. Electrolytes: Hypokalemia

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