Human Immunodeficiency Virus Book

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Integrase Strand Transfer Inhibitor

Aka: Integrase Strand Transfer Inhibitor, Raltegravir, Isentress, InSTI, RAL
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  1. See Also
    1. Anti-Retroviral Therapy
  2. Class
    1. Anti-retroviral agent
    2. Integrase Strand Transfer Inhibitor
  3. Mechanism
    1. Integrase Strand Transfer Inhibitor prevents viral DNA from integrating into host DNA
      1. Blocks the integrase enzyme
  4. Indications
    1. Anti-retroviral naive patients
    2. Anti-retroviral experienced patients
  5. Dosing
    1. Orally twice daily
  6. Efficacy
    1. Drug resistance is common
  7. Adverse Effects
    1. Diarrhea
    2. Nausea
    3. Headache
    4. Serum Creatinine phosphokinase (CPK) increases
    5. Myopathy
    6. Rhabdomyolysis
  8. References
    1. (2009) Treat Guidel Med Lett 7(78): 11-22
    2. Reust (2011) Am Fam Physician 83(12): 1443-51
Medication Costs
HYDRALAZINE (on 2/10/2012 at Target.com)
HYDRALAZINE 10 MG Tablet #30 for $4.00 ($0.13/unit)
HYDRALAZINE 25 MG Tablet #30 for $4.00 ($0.13/unit)
Isentress (on 2/9/2012 at DrugStore.com)
Isentress 60 400mg Tablets Bottle #1 for $1014.93 ($1014.93/unit)
Megace Oral (on 2/9/2012 at DrugStore.com)
Megace Oral 40mg/ml Suspension #240 for $167.99 ($0.70/unit)
Aralen (on 2/9/2012 at DrugStore.com)
Aralen 500mg Tablets #25 for $190.00 ($7.60/unit)
Uroxatral (on 2/9/2012 at DrugStore.com)
Uroxatral 10mg 24 Hour Tablets #30 for $142.99 ($4.77/unit)
Doral (on 2/9/2012 at DrugStore.com)
Doral 7.5mg Tablets #30 for $100.98 ($3.37/unit)
Doral 15mg Tablets #30 for $127.99 ($4.27/unit)
Neoral (on 2/9/2012 at DrugStore.com)
Neoral 30 25mg Capsules Box #2 for $91.99 ($46.00/unit)
Neoral 30 100mg Capsules Box #1 for $185.98 ($185.98/unit)
Neoral 100mg/ml Solution 50ml Bottle #1 for $335.99 ($335.99/unit)
Desferal (on 2/9/2012 at DrugStore.com)
Desferal 500mg Solution Vial #4 for $111.34 ($27.84/unit)
Sucralfate (on 2/9/2012 at DrugStore.com)
Sucralfate 1gm/10ml Suspension #10 for $13.99 ($1.40/unit)
Sucralfate 1gm Tablets #90 for $41.99 ($0.47/unit)
Ferralet 90 (on 2/9/2012 at DrugStore.com)
Ferralet 90 90-1mg Tablets #30 for $37.99 ($1.27/unit)
Oxsoralen Ultra (on 2/9/2012 at DrugStore.com)
Oxsoralen Ultra 10mg Capsules #30 for $1300.01 ($43.33/unit)
Campral (on 2/9/2012 at DrugStore.com)
Campral 333mg Enteric Coated Tabs #180 for $162.99 ($0.91/unit)
K-Phos-Neutral (on 2/9/2012 at DrugStore.com)
K-Phos-Neutral 155-852-130mg Tablets #30 for $18.99 ($0.63/unit)
Adderall (on 2/9/2012 at DrugStore.com)
Adderall 5mg Tablets #20 for $80.99 ($4.05/unit)
Adderall 10mg Tablets #20 for $85.99 ($4.30/unit)
Adderall 15mg Tablets #20 for $77.99 ($3.90/unit)
Adderall 20mg On Manufacturer Backorder Until January 2012. #20 for $84.99 ($4.25/unit)
Adderall 30mg Tablets #20 for $80.99 ($4.05/unit)
Aquoral (on 2/9/2012 at DrugStore.com)
Aquoral Aerosol 40ml Can #1 for $109.99 ($109.99/unit)
Keralac (on 2/9/2012 at DrugStore.com)
Keralac 50% Ointment 45gm Tube #1 for $139.98 ($139.98/unit)
Keralac 50% Cream 142gm Tube #1 for $195.99 ($195.99/unit)
Keralac 50% Gel 18ml Bottle #1 for $264.61 ($264.61/unit)
Keralac 35% Lotion 325ml Bottle #1 for $305.00 ($305.00/unit)
Keralyt (on 2/9/2012 at DrugStore.com)
Keralyt 6% Gel 40gm Tube #1 for $55.99 ($55.99/unit)
Atralin (on 2/9/2012 at DrugStore.com)
Atralin 0.05% Gel 45gm Tube #1 for $250.69 ($250.69/unit)
Inderal LA (on 2/9/2012 at DrugStore.com)
Inderal LA 60mg 24 Hour Capsule #30 for $155.99 ($5.20/unit)
Inderal LA 120mg 24 Hour Capsule #30 for $182.00 ($6.07/unit)
Inderal LA 160mg 24 Hour Capsule #30 for $263.99 ($8.80/unit)
Lo/Ovral (28) (on 2/9/2012 at DrugStore.com)
Lo/Ovral (28) 28 0.3-30mg-mcg Tablets Disp Pack #1 for $59.99 ($59.99/unit)
Sertraline HCl (on 2/9/2012 at DrugStore.com)
Sertraline HCl 25mg Tablets #30 for $19.99 ($0.67/unit)
Sertraline HCl 50mg Tablets #30 for $12.99 ($0.43/unit)
Sertraline HCl 100mg Tablets #30 for $15.99 ($0.53/unit)
Sertraline HCl 20mg/ml Concentrate 60ml Bottle #1 for $62.99 ($62.99/unit)
HydrALAZINE HCl (on 2/9/2012 at DrugStore.com)
HydrALAZINE HCl 10mg Tablets #30 for $14.99 ($0.50/unit)
HydrALAZINE HCl 50mg Tablets #30 for $20.99 ($0.70/unit)
HydrALAZINE HCl 100mg Tablets #30 for $25.99 ($0.87/unit)
HydrALAZINE HCl 25mg Tablets #100 for $27.99 ($0.28/unit)
MiraLax (on 2/9/2012 at DrugStore.com)
MiraLax Powder 119gm Bottle #1 for $15.99 ($15.99/unit)
Safyral (on 2/9/2012 at DrugStore.com)
Safyral 28 3-0.03-0.451mg Tablets Disp Pack #1 for $90.88 ($90.88/unit)
Nizoral (on 2/9/2012 at DrugStore.com)
Nizoral 200mg Tablets #30 for $129.99 ($4.33/unit)
Nizoral 2% Shampoo 120ml Bottle #1 for $53.99 ($53.99/unit)
Adderall XR (on 2/9/2012 at DrugStore.com)
Adderall XR 5mg 24 Hour Capsule #20 for $156.99 ($7.85/unit)
Adderall XR 10mg 24 Hour Capsule #20 for $158.26 ($7.91/unit)
Adderall XR 15mg 24 Hour Capsule #20 for $162.00 ($8.10/unit)
Adderall XR 20mg 24 Hour Capsule #20 for $158.26 ($7.91/unit)
Adderall XR 25mg 24 Hour Capsule #20 for $158.26 ($7.91/unit)
Adderall XR 30mg 24 Hour Capsule #20 for $158.26 ($7.91/unit)
Mebaral (on 2/9/2012 at DrugStore.com)
Mebaral 32mg Tablets #100 for $87.99 ($0.88/unit)
Mebaral 50mg Tablets #100 for $126.99 ($1.27/unit)
Mebaral 100mg Tablets #100 for $169.98 ($1.70/unit)
Sectral (on 2/9/2012 at DrugStore.com)
Sectral 200mg Capsules #60 for $179.98 ($3.00/unit)
Sectral 400mg Capsules #30 for $125.00 ($4.17/unit)
FPNotebook does not benefit financially from showing this medication data or their pharmacy links. This information is provided only to help medical providers and their patients see relative costs. Insurance plans negotiate lower medication prices with suppliers. Prices shown here are out of pocket, non-negotiated rates. See Needy Meds for financial assistance information.

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