Endocrinology Book

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Endocrine Medications in Pregnancy

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  1. See Also
    1. Medications in Pregnancy
    2. Gestational Diabetes
  2. Class A: No risk in controlled human studies
    1. Dessicated Thyroid (Armour Thyroid)
    2. Levothyroxine (T4 or Synthroid)
    3. Liothyronine (T3 or Cytomel)
  3. Class B: No risk in controlled animal studies
    1. Acarbose (Precose)
    2. Calcitonin
    3. Insulin
    4. Metformin (Glucophage)
    5. Prednisone
    6. Prednisolone
  4. Class C: Small risk in controlled animal studies
    1. Acetohexamide
    2. Beclomethasone
    3. Betamethasone
    4. Bromocriptine
    5. Chlorpropamide (Diabinase)
    6. Dexamethasone
    7. Glipizide (Glucotrol)
    8. Glyburide (Micronase or DiaBeta)
    9. Triamcinolone
  5. Class D: Strong evidence of risk to the human fetus
    1. Lynestrenol
    2. Medroxyprogesterone
    3. Methimazole
    4. Propylthiouracil (preferred over Methimazole)
    5. Tamoxifen
    6. Tolbutamide (Orinase)
  6. Class X: Very high risk to the human fetus
    1. Clomiphene (Clomid)
    2. Danazol
    3. Diethylstilbesterol (DES)
    4. Estrogens (all)
    5. Iodide I-131
    6. Leuprolide (Leupron)
    7. Norethindrone
    8. Norethynodrel
    9. Norgestrel
    10. Oral Contraceptives
  7. References
    1. Briggs (1998) Drugs in Pregnancy and Lactation, 5th ed
    2. Larimore (2000) Prim Care 27(1):35

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