Third Generation Progestin

Aka: Third Generation Progestin, Norgestrel, Levonorgestrel

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II. Class

  1. 19 Nor-TestosteroneProgestin: Gonane

III. Preparation: dl-Norgestrel

  1. Relative Progestational Activity: 2.6
    1. Estrogenic Activity: 0
    2. Androgenic Activity: 4.2
    3. Endometrial Activity: 2.6
    4. Anti-Estrogen: Active
    5. Anabolic: Active
  2. Preparations
    1. Ethinyl Estradiol
      1. Lo-Ovral (0.3/30)
      2. Ovral (0.5/50)
    2. Progesterone Only OCP (Mini-Pill)
      1. Ovrette (0.075)

IV. Preparation: Levonorgestrel

  1. Relative Progestational Activity: 5.3
    1. Estrogenic Activity: 0
    2. Androgenic Activity: 8.3
    3. Endometrial Activity: 5.1
    4. Anti-Estrogen: Active
    5. Anabolic: Active
  2. Preparations with Ethinyl Estradiol
    1. Alesse (0.1/20)
    2. Nordette (0.15/30)
    3. Monofeme (0.15/30)
    4. Levlen (0.15/30)
    5. Triphasil (0.05/30 - 0.075/40 - 0.125/30)
    6. Seasonale (0.15/30) - Seasonal Contraception
    7. Lybrel (0.09/20) - continuous

V. Adverse Effects

  1. See Oral Contraceptive
  2. Higher risk of Thromboembolism than other OCPs

VI. References

  1. Cerel-Suhl (1999) Am Fam Physician 60(7):2073 [PubMed]
  2. Speroff (1993) Obstet Gynecol 81:1034-47 [PubMed]
  3. Dickey (1998) Managing Contraceptive Pill Patients

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Related Studies

Cost: Medications

levonorgestrel (on 12/21/2022 at Medicaid.Gov Survey of pharmacy drug pricing)
LEVONORGESTREL 1.5 MG TABLET Generic OTC $8.63 each
LEVONORGESTREL-ETH ESTRAD 0.15 MG-0.03 MG TABLET Generic $0.17 each
LEVONORGESTREL-ETH ESTRADIOL-FE BISGLYC 0.1-0.02-36.5 MG TAB Generic $8.27 each
FPNotebook does not benefit financially from showing this medication data or their pharmacy links. This information is provided only to help medical providers and their patients see relative costs. Insurance plans negotiate lower medication prices with suppliers. Prices shown here are out of pocket, non-negotiated rates. See Needy Meds for financial assistance information. GoodRx is another tool for finding lower drug prices.

Related Topics in Pharmacology

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