Cardiovascular Medicine Book

Circulatory Disorders

http://www.fpnotebook.com/

High Risk Acute Coronary Syndrome ManagementAka: ST Elevation MI, Q-Wave MI, Myocardial Infarction Protocol

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  1. See Also
    1. MI Adjunctive Therapy
  2. Criteria: Myocardial Infarction
    1. ST Elevation 1 mm or more in 2 or more contiguous leads
    2. New Left Bundle Branch Block obscuring ST segments
    3. Presumed new Left Bundle Branch Block
  3. Management: Protocol
    1. Time from Chest Pain onset <12 hours
      1. Start MI Adjunctive Therapy, do not delay reperfusion
      2. Immediate Reperfusion Strategy
        1. Angioplasty with cardiothoracic back-up (preferred)
          1. Goal within 90 minutes of ED arrival
        2. Thrombolytic therapy (if Angioplasty not available)
          1. Goal within 30 minutes of ED arrival
        3. Efficacy: Comparing Angioplasty with Thrombolytic
          1. Similar outcomes and complication rates
            1. Mehta (2002) J Am Coll Cardiol 40:1034
          2. Angioplasty preferred if transport delay <1 hour
            1. Andersen (2003) N Engl J Med 349:733
    2. Time from Chest Pain onset >12 hours
      1. Manage as Myocardial Ischemia Protocol
  4. References
    1. (2000) Circulation 102(suppl I):I

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