Benzodiazepine Equivalents

Aka: Benzodiazepine Equivalents, Barbiturate Equivalents, Sedative Equivalents

1. Indications
   1. Benzodiazepine Withdrawal
   2. Barbiturate withdrawal
   3. Sedative withdrawal
2. General
   1. Equivalents to 60 mg Diazepam or 180 mg Phenobarbital
   2. Equivalent = drug dose X Conversion factor
3. Benzodiazepines Equivalents to Diazepam 60 mg
   1. Alprazolam (Xanax) 6 mg
      1. Valium = Dose x10
      2. Phenobarbital = Dose x30
   2. Chlordiazepoxide (Limbitrol) 150 mg
      1. Valium = Dose x0.4
      2. Phenobarbital = Dose x1.2
   3. Clonazepam (Klonopin) 24 mg
      1. Valium = Dose x2.5
      2. Phenobarbital = Dose x7.5
   4. Flurazepam (Dalmane) 90 mg
      1. Valium = Dose x 0.6
      2. Phenobarbital = Dose x2.0
   5. Halazepam (Paxipam) 240 mg
      1. Valium = Dose x0.25
      2. Phenobarbital = Dose x0.75
   6. Lorazepam (Ativan) 12 mg
      1. Valium = Dose x5.0
      2. Phenobarbital = Dose x15.0
   7. Oxazepam (Serax) 60 mg
      1. Valium = Dose x1.0
      2. Phenobarbital = Dose x3.0
   8. Temazepam (Restoril) 60 mg
      1. Valium = Dose x1.0
      2. Phenobarbital = Dose x3.0
4. Barbiturate Equivalents to Phenobarbital 180 mg
   1. Butabarbital (Butisol) 600 mg
      1. Valium = Dose x0.1
      2. Phenobarbital = Dose x0.3
   2. Pentobarbital (Nembutal) 600 mg
      1. Valium = Dose x0.1
      2. Phenobarbital = Dose x0.3
   3. Secobarbital (Seconal) 600 mg
      1. Valium = Dose x0.1
      2. Phenobarbital = Dose x0.3
   4. Phenobarbital 180 mg
      1. Valium = Dose x0.33
      2. Phenobarbital = Dose x1.0
5. Miscellaneous Sedative Equivalents
   1. Glycerol: Meprobamate (Equanil) 2400 mg
      1. Valium= Dose x0.025
      2. Phenobarbital = Dose x0.075
   2. Piperidinedione: Glutethimide (Doriden) 1500 mg
      1. Valium = Dose x0.04
      2. Phenobarbital = Dose x0.12
   3. Quinazoline: Methaqualone 1800 mg
      1. Valium = Dose x0.03
      2. Phenobarbital = Dose x0.1