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Chlordiazepoxide

Aka: Chlordiazepoxide, Librium
  1. See Also
    1. Benzodiazepine
  2. Class
    1. Long Acting Benzodiazepine
  3. Pharmacokinetics
    1. Half Life: 7-48 hours
  4. Dosing
    1. Anxiety Disorder
      1. Oral: 5 to 25 mg PO tid to qid
      2. Parenteral: 25 to 50 mg IM or IV tid to qid
    2. Alcohol Withdrawal
      1. Dose: 50 to 100 mg PO, IM or IV
      2. Repeat dosing every 3-4 hours up to 300 mg per day

Librium (C0013881)

Concepts Organic Chemical (T109) , Pharmacologic Substance (T121)
MSH D002707
English librium, Librium
Sources
Derived from the NIH UMLS (Unified Medical Language System)


Chlordiazepoxide (C0008188)

Definition (MSH) An anxiolytic benzodiazepine derivative with anticonvulsant, sedative, and amnesic properties. It has also been used in the symptomatic treatment of alcohol withdrawal.
Definition (CSP) anxiolytic benzodiazepine derivative with anticonvulsant, sedative, and amnesic properties; also used in the symptomatic treatment of alcohol withdrawal.
Definition (NCI) A long-acting benzodiazepine with anxiolytic, sedative and hypnotic activity. Chlordiazepoxide exerts its effect by binding to the benzodiazepine site at the gamma-aminobutyric acid (GABA) receptor-chloride ionophore complex in the central nervous system (CNS). This leads to an increase in the opening of chloride channels, membrane hyperpolarization and increases the inhibitory effect of GABA on the CNS.
Concepts Organic Chemical (T109) , Pharmacologic Substance (T121)
MSH D002707
SnomedCT 372866006, 82746003
English Methaminodiazepoxide, 7 Chloro N methyl 5 phenyl 3H 1,4 benzodiazepin 2 amine 4 oxide, 7-Chloro-N-methyl-5-phenyl-3H-1,4-benzodiazepin-2-amine 4-oxide, 3H-1,4-Benzodiazepin-2-amine, 7-chloro-N-methyl-5-phenyl-, 4-oxide, 3H-1,4-Benzodiazepin-2-amine, 7-chloro-N-methyl-5-phenyl, 4-oxide, chlordiazepoxide, chlordiazepoxide (discontinued), chlordiazepoxide (discontinued) (medication), Chlordiazepoxide, CHLORDIAZEPOXIDE, Chlordiazepoxide [Chemical/Ingredient], methaminodiazepoxide, chlordiazePOXIDE, Chlordiazepoxide (product), Chlordiazepoxide (substance)
Swedish Klordiazepoxid
Czech chlordiazepoxid
Finnish Klooridiatsepoksidi
Russian KHLOZEPID, LIBRIUM, NAPOTON, KHLORDIAZEPOKSID, METAMINODIAZEPOKSID, ELENIUM, ЛИБРИУМ, МЕТАМИНОДИАЗЕПОКСИД, НАПОТОН, ХЛОЗЕПИД, ХЛОРДИАЗЕПОКСИД, ЭЛЕНИУМ
Japanese クロルジアゼポキシド, メタミノジアゼポキシド
Italian Metaminodiazepossido, Clordiazepossido
Croatian KLORDIAZEPOKSID
Spanish clordiacepóxido (producto), clordiacepóxido, clordiazepóxido, clordiazepóxido (sustancia), clordiazepóxido (producto), Metaminodiazepóxido, Clorodiacepóxido, Metaminodiazepoxido, Metaminodiacepóxido, Clorodiazepoxido, Clordiacepóxido, Clordiacepoxido, Clorodiacepoxido, Clorodiazepóxido, Metaminodiacepoxido, clordiacepóxido (sustancia), Clordiazepoxido, Librium, Clordiazepóxido
Polish Chlordiazepoksyd, Elenium, Librium
French Chlordiazépoxyde
German Chlordiazepoxid, Methaminodiazepoxid
Portuguese Clordiazepóxido, Librium, Metaminodiazepóxido
Sources
Derived from the NIH UMLS (Unified Medical Language System)


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