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HalazepamAka: Paxipam

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  1. See Also
    1. Benzodiazepine
  2. Indication
    1. Anxiety Disorder
  3. Class
    1. Long acting Benzodiazepine
  4. Pharmacokinetics
    1. Peak plasma concentration: 1-3 hours after oral dose
    2. Half Life: 14 hours
  5. Dosing
    1. Dose: 20 to 40 mg PO tid to qid or 80 mg PO qhs
    2. Maximum Daily Dose: 160 mg
  6. Equivalent Dosing (for Benzodiazepine Withdrawal)
    1. Valium = Halazepam Dose x0.25
    2. Phenobarbital = Halazepam Dose x0.75

halazepam (C0062092)

Definition (NCI)A synthetic benzodiazepine derivative with anxiolytic property. Halazepam potentiates the inhibitory activities of gamma-aminobutyric acid (GABA) by binding to the benzodiazepine-GABA-A-chloride ionophore receptor complex located in the limbic, thalamic and hypothalamic regions of the central nervous system (CNS). This increases the frequency of chloride channel opening, allowing the flow of chloride ions into the neuron and ultimately leading to membrane hyperpolarization and a decrease in neuronal excitability.
ConceptsOrganic Chemical (T109) , Pharmacologic Substance (T121)
MSHC010175
Englishhalazepam, HALAZEPAM PREPARATION, Halazepam product
Spanishhalacepam, halazepam
Parent ConceptsBenzodiazepinones (C0005065), Benzodiazepines (C0005064), [CN302] BENZODIAZEPINE DERIVATIVE, SEDATIVES/HYPNOTICS (C0973503), Unclassified Ingredients (C1372954)
SourcesAOD, LNC, MSH, NCI, NDFRT, RXNORM, SCTSPA, SNOMEDCT, VANDF
Derived from the NIH UMLS (Unified Medical Language System)


Paxipam (C0722503)

ConceptsOrganic Chemical (T109) , Pharmacologic Substance (T121)
EnglishPaxipam
SourcesNCI, RXNORM
Derived from the NIH UMLS (Unified Medical Language System)



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