II. Definition

  1. Decreased Saliva production

III. Physiology: Saliva plays vital role in Dental Health

  1. Re-mineralizes enamel
  2. Buffers cariogenic acids
  3. Removes food residue
  4. Inhibits Bacterial growth

V. Management

  1. Consider stopping offending medication
  2. Commercial Saliva substitute (typically carboxymethylcellulose, mucin or Glycerine)
  3. Directly apply fluoride to teeth and in Toothpaste
    1. Use 1.1% Fluoride gel daily
    2. Fluoride toothpaste
    3. Fluoride rinses
  4. Scrupulous dental care is essential
    1. See Dentist regularly
  5. Saliva stimulation
    1. Sugar-free chewing gum (esp. Xylitol containing gums)
    2. Lemon lozenges
  6. Consider Muscarinic Agonists in severe refractory Xerostomia of Sjogren's Syndrome
    1. Pilocarpine (Salagen)
    2. Cevimeline (Evoxac)

VI. References

  1. Daniels in Goldman (2000) Cecil Medicine, p. 2245

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Ontology: Xerostomia (C0043352)

Definition (MEDLINEPLUS)

Dry mouth is the feeling that there is not enough saliva in your mouth. Everyone has a dry mouth once in a while - if they are nervous, upset or under stress. But if you have a dry mouth all or most of the time, it can be uncomfortable and can lead to serious health problems.

Symptoms of dry mouth include

  • A sticky, dry feeling in the mouth
  • Trouble chewing, swallowing, tasting, or speaking
  • A burning feeling in the mouth
  • A dry feeling in the throat
  • Cracked lips
  • A dry, rough tongue
  • Mouth sores
  • An infection in the mouth

Dry mouth is not a normal part of aging. Causes include some medicines, radiation therapy, chemotherapy, and nerve damage. Salivary gland diseases, Sjogren's syndrome, HIV/AIDS, and diabetes can also cause dry mouth.Treatment depends on the cause. Things you can do include sipping water, avoiding drinks with caffeine, tobacco, and alcohol, and chewing sugarless gum or sucking on sugarless hard candy.

NIH: National Institute of Dental and Craniofacial Disorders

Definition (NCI_NCI-GLOSS) Dry mouth. It occurs when the body is not able to make enough saliva.
Definition (NCI_CTCAE) A disorder characterized by reduced salivary flow in the oral cavity.
Definition (NCI) An oral condition in which salivary flow is reduced.
Definition (CSP) dryness of the mouth due to salivary gland secretion dysfunction.
Definition (MSH) Decreased salivary flow.
Concepts Sign or Symptom (T184)
MSH D014987
ICD10 K11.7
SnomedCT 162014002, 196513007, 249425009, 139281004, 266425004, 87715008, 56893005
LNC MTHU013517
English Asialia, Asialias, Hyposalivation, Hyposalivations, Mouth Dryness, Xerostomia, Xerostomias, APTYALISM, Dryness, Mouth, MOUTH DRY, ORAL DRYNESS, SALIVA DECREASED, XEROSTOMIA, dry mouth, mouth dryness (symptom), mouth dryness (xerostomia), mouth dryness, xerostomia (physical finding), xerostomia, salivary secretion disturbance: xerostomia, xerostomia (diagnosis), xerostomia was observed, Mouth became dry, Saliva decreased, Mouth dry, Dryness oral, Oral dryness, Xerostomia [Disease/Finding], decreased saliva, dryness mouth, Dry;mouth, drying mouth, hyposalivation, mouth dry, Dry Mouth, (Dry mouth) or (salivary hyposecretion) (disorder), Salivary hyposecretion (disorder), Dry mouth (finding), (Dry mouth) or (salivary hyposecretion), Dry mouth, Aptyalism, Absent salivary secretion, Aptyalia, Hyposecretion of salivary gland, Salivary hyposecretion, Clinical xerostomia, Hypoactive salivary flow, Hyposecretion of salivary gland (disorder), Inadequate salivary flow, Aptyalism (disorder), asialia, aptyalism, hyposecretion; salivary gland, mouth; dry, salivary gland; hyposecretion, Salivary hyposecretion [Ambiguous]
French XEROSTOMIE, Hyposécrétion salivaire, Bouche devenue sèche, Sécherese orale, Salive diminuée, APTYALISME, HYPO-SIALORRHEE, SECHERESSE BUCCALE, SECHERESSE DE LA BOUCHE, Bouche sèche, Xérostomie, Aptyalisme, Asialie, Hypoptyalisme, Sècheresse de la bouche, Sécheresse buccale
Portuguese XEROSTOMIA, SECURA DA BOCA, Secura da boca, Hipossecreção salivar, Boca ressequida, Saliva diminuída, APTIALISMO, DIMINUICAO DA SALIVA, SECURA ORAL, Aptialismo, Boca seca, Assialia, Hiposalivação, Secura da Boca, Xerostomia
Spanish XEROSTOMIA, Sequedad de boca, Saliva disminuida, Ptialina, Hiposecreción salival, APTIALISMO, BOCA SECA, SALIVA DISMINUIDA, SEQUEDAD DE BOCA, Sequedad Bucal, aptialismo, asialia, boca seca, flujo salival hipoactivo, flujo salival inadecuado, hiposalivación, hiposecreción de la glándula salival (trastorno), hiposecreción de la glándula salival, secreción salival ausente, xerostomía (trastorno), xerostomía, Aptialismo, Boca seca, Asialia, Boca Seca, Hiposalivación, Xerostomía
German XEROSTOMIE, Trockenheit des Mundes, orale Trockenheit, Mund wurde trocken, Speichel vermindert, Mund trocken, verminderte Speichelsekretion, APTYALISMUS, MUNDTROCKENHEIT, SPEICHEL VERMINDERT, TROCKENHEIT MUND, Aptyalismus, Asialie, Hyposalivation, Mundtrockenheit, Xerostomie
Italian Aptialismo, Bocca secca, Secchezza della bocca, Secchezza orale, Aptialia, Bocca diventata secca, Iposecrezione salivare, Saliva diminuita, Bocca asciutta, Asialia, Iposalivazione, Xerostomia
Dutch mond die droog wordt, orale droogheid, xerostomie, asialie, speeksel gedaald, speeksel hyposecretie, hyposecretie; speekselklier, mond; droog, speekselklier; hyposecretie, aptyalisme, droge mond, Asialia, Droge mond, Hyposalivatie, Mond, droge, Xerostomie
Japanese 唾液減少, 唾液欠乏, 口腔乾燥, 唾液分泌低下, ダエキケツボウ, ダエキゲンショウ, コウナイカンソウ, ダエキブンピテイカ, コウコウカンソウ, ダエキブンピツテイカ, コウクウカンソウ, 口腔乾燥症, 口内乾燥症, 口渇(口内乾燥症), 口内乾燥, 唾液分泌不全症(ダエキブンピツフゼンショウ), 唾液分泌欠如, 唾液減少症, 唾液分泌不全症
Swedish Muntorrhet
Czech xerostomie, Vyschlá ústa, Snížení produkce slin, Xerostomie, Suchá ústa, Suchost úst, Aptyalismus, Hyposekrece slin, suchost v ústech, hyposalivace
Finnish Suun kuivuus
Russian GIPOSIALIIA, KSEROSTOMIIA, GIPOSALIVATSIIA, APTIALIZM, ASIALIIA, OLIGOPTIALIZM, АПТИАЛИЗМ, АСИАЛИЯ, ГИПОСАЛИВАЦИЯ, ГИПОСИАЛИЯ, КСЕРОСТОМИЯ, ОЛИГОПТИАЛИЗМ
Croatian KSEROSTOMIJA
Polish Kserostomia, Suchość jamy ustnej
Hungarian Xerostomia, Nyálhiány, Szájkiszáradás, Szájszárazság, Asialia, Száraz száj, Nyál csökkenés, Száj szárazság, Nyál hyposecretio, Aptialismus, Oralis szárazság
Norwegian Xerostomi, Tørr munn, Munntørrhet

Ontology: Reduced salivation (C0576990)

Concepts Finding (T033)
SnomedCT 300268000
English Salivation decreased, Reduced salivation, Reduced salivation (finding)
Spanish salivación reducida (hallazgo), salivación reducida