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Dry MouthAka: Xerostomia, Salivary Hypofunction, Decreased Saliva Secretion

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  1. Definition
    1. Decreased Saliva production
  2. Physiology: Saliva plays vital role in Dental Health
    1. Re-mineralizes enamel
    2. Buffers cariogenic acids
    3. Removes food residue
    4. Inhibits bacterial growth
  3. Causes
    1. Medications (anticholinergic affect)
      1. Tricyclic Antidepressants
      2. Antispasmodics
      3. Neuroleptics
      4. MAO inhibitors
      5. Antiparkinsonian agents
      6. Lithium
      7. Central Adrenergic Agonists (antihypertensives)
      8. Diuretics
      9. Decongestants
      10. Antihistamines
      11. Bronchodilators
    2. Other causes:
      1. Radiation therapy to head and neck
      2. Salivary Gland surgery
      3. Sjogren's Syndrome
      4. Amyloidosis
      5. Human Immunodeficiency Virus (HIV Infection)
      6. Diabetes Mellitus
      7. Major Depression
      8. Granulomatous Disease
        1. Sarcoidosis
        2. Tuberculosis
        3. Leprosy
  4. Management
    1. Consider stopping offending medication
    2. Commercial Saliva substitute
    3. Fluoride Supplementation
      1. Use 1.1% Fluoride gel daily
      2. Fluoride toothpaste
    4. Scrupulous dental care is essential
  5. References
    1. Daniels in Goldman (2000) Cecil Medicine, p. 2245

Xerostomia (C0043352)

Definition (MSH)Decreased salivary flow.
Definition (NCI)Dry mouth. It occurs when the body is not able to make enough saliva.
Definition (CSP)dryness of the mouth due to salivary gland secretion dysfunction.
Definition (NCI)An oral condition in which salivary flow is reduced. --2004
ConceptsDisease or Syndrome (T047)
ICD9527.7
EnglishAbsent salivary secretion, Aptyalia, Aptyalism, Asialia, Asialias, Clinical xerostomia, Dry Mouth, DRYNESS ORAL, Hypoactive salivary flow, Hyposalivation, Hyposalivations, Hyposecretion of salivary gland, Inadequate salivary flow, MOUTH DRY, MOUTH DRYNESS, ORAL DRYNESS, SALIVA DECREASED, Salivary hyposecretion, Xerostomia, Xerostomias
Spanishaptialismo, asialia, boca seca, flujo salival hipoactivo, flujo salival inadecuado, hiposalivación, hiposalivacion, hiposecreción de la glándula salival, hiposecrecion de la glandula salival, secreción salival ausente, secrecion salival ausente, xerostomía, xerostomia
CreditsDerived from the NIH UMLS (Unified Medical Language System)



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