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Blood Urea NitrogenAka: BUN

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  1. Pathophysiology
    1. Increases by 10-20 mg/dl/day if Renal Function absent
    2. Serum Creatinine is a better measure of Renal Function
      1. BUN is Protein dependent
        1. High protein diet
        2. Catabolism
      2. BUN is reabsorbed at renal tubules
        1. Prerenal Failure
          1. Dehydration
          2. Congestive Heart Failure
        2. Postrenal Failure
          1. Obstructive Uropathy
  2. Increased BUN
    1. Medications
      1. Aminoglycosides
      2. Diuretics
      3. Lithium
      4. Corticosteroids
    2. Dehydration
    3. Gastrointestinal Bleeding
    4. Decreased Renal blood flow
      1. Shock
      2. Congestive Heart Failure
      3. Myocardial Infarction
    5. Renal disease
      1. Glomerulonephritis
      2. Pyelonephritis
      3. Diabetic Nephropathy
    6. Urinary Tract Obstruction
  3. Decreased BUN
    1. Liver disease
    2. Poor nutrition
    3. Overhydration
    4. Third trimester of pregnancy

Blood urea nitrogen measurement (C0005845)

Definition (MSH)The urea concentration of the blood stated in terms of nitrogen content. Serum (plasma) urea nitrogen is approximately 12% higher than blood urea nitrogen concentration because of the greater protein content of red blood cells. Increases in blood or serum urea nitrogen are referred to as azotemia and may have prerenal, renal, or postrenal causes. (From Saunders Dictionary & Encyclopedia of Laboratory Medicine and Technology, 1984)
Definition (NCI)A measurement of the urea nitrogen in a blood specimen.
Definition (NCI)A quantitative measurement of the amount of urea nitrogen present in a sample of serum.
ConceptsLaboratory Procedure (T059)
EnglishBlood urea, Blood urea measurement, Blood Urea Nitrogen, Blood urea nitrogen measurement, BUN, BUN measurement
Spanishdeterminación de uremia, determinacion de uremia, medición de BUN, medición de nitrógeno ureico en sangre, medición de NUS, medición de uremia, medicion de BUN, medicion de nitrogeno ureico en sangre, medicion de NUS, medicion de uremia
CreditsDerived from the NIH UMLS (Unified Medical Language System)



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