II. Signs: Skin findings suggestive of infectious pathology

  1. Petechiae or Purpura (Systemic Vasculitis)
  2. Seborrheic rash (Histiocytosis X)
  3. Perineal rash (Kawasaki's Disease)
  4. Pallor, Jaundice or soft skin (Hyperthyroidism)
  5. Sparse eyebrows (anhydrotic ectodermal dysplasia)
  6. Hair Loss or breakage (Systemic Lupus Erythematosus)
  7. Characteristic rashes
    1. Tick-borne infection (e.g. Lyme Disease)
    2. Herpes Simplex Virus

V. Signs: Musculoskeletal findings

  1. Joint Swelling or pain
    1. Inflammatory Bowel Disease
    2. Lyme Disease
  2. Bone findings suggestive of infectious pathology
    1. See Osteomyelitis
    2. Focal tenderness (assess for long bone Osteomyelitis)

VI. Signs: Lymph node findings suggestive of infectious pathology

  1. Generalized Lymphadenopathy
    1. Autoimmune cause
    2. Cat Scratch Disease
    3. Cytomegalovirus
    4. Epstein-Barr Virus
    5. Acute HIV Infection
  2. Localized or nontender adenopathy
    1. Malignancy

VII. Signs: Cardiac findings suggestive of infectious pathology

  1. Diastolic insufficiency murmurs
  2. Widened Pulse Pressure

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