Pulmonology Book

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Extrapulmonary TuberculosisAka: Disseminated tuberculosis, Miliary Tuberculosis

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  1. Areas of dissemination
    1. Tuberculous Lymphadenitis (most common form)
    2. Pleural Tuberculosis (5%)
    3. Skeletal Tuberculosis (35%)
    4. Tuberculous Meningitis
      1. CSF with moderate lymphcytosis
    5. Gastrointestinal Tuberculosis
    6. Genitourinary Tuberculosis
    7. Tuberculous Peritonitis
    8. Miliary Tuberculosis
    9. Tuberculous Pericarditis
    10. Miliary Tuberculosis (disseminated Tuberculosis)
      1. Seen in AIDS and untreated Tuberculosis
      2. Presents with fever, Night Sweats, weight loss
      3. PPD is positive in only 50% of cases
  2. Management
    1. Duration of therapy (phase 1 and 2 combined)
      1. Most forms of extrapulmonary Tuberculosis: 4-7 months
      2. CNS Tuberculosis: 9-12 months
      3. Musculoskeletal Tuberculosis: Extended duration
    2. Phase 1: First 2 months (altered if suspect resistance)
      1. Isoniazid
      2. Rifampin
      3. Pyrazinamide
      4. Ethambutol
    3. Phase 2: Duration varies per guidelines above
      1. Isoniazid
      2. Rifampin
  3. References
    1. Golden (2005) Am Fam Physician 72(9):1761

Tuberculosis, Miliary (C0041321)

Definition (MSH)An acute form of TUBERCULOSIS in which minute tubercles are formed in a number of organs of the body due to dissemination of the bacilli through the blood stream.
ConceptsDisease or Syndrome (T047)
ICD9018, 018.9, 018.90
MSHD014391
EnglishMiliary Tuberculoses, Miliary tuberculosis, MTB - Miliary tuberculosis, Unspecified miliary tuberculosis
Spanishtuberculosis miliar
Parent ConceptsTuberculosis (C0041296), Tuberculosis, Miliary (C0041321), [X]Acute miliary tuberculosis, unspecified (C0152915), Duplicate concept (C1274013)
SourcesDXP, ICD9CM, MSH, NCI, NDFRT, SCTSPA, SNOMEDCT
Derived from the NIH UMLS (Unified Medical Language System)


Tuberculosis, extrapulmonary (C0679362)

ConceptsDisease or Syndrome (T047)
Englishextrapulmonary tuberculosis
SpanishTB extrapulmonar, tuberculosis extrapulmonar
Parent ConceptsTuberculosis (C0041296)
SourcesAOD, SCTSPA, SNOMEDCT
Derived from the NIH UMLS (Unified Medical Language System)



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