Hematology and Oncology Book

Lymphatic Disorders

Coagulopathy

Anemia

Cancer

Complete Blood Count

Platelet Disorders

Hemolytic Disorders

Bone Marrow Disorders

Peripheral

Acute Phase Reactant

SPEP

Pharmacology Chapter related topics

Infectious Disease Chapter related topics

http://www.fpnotebook.com/

Neutropenia Causes

Aka: Neutropenia Causes, Agranulocytosis Causes
Advertisement
  1. See Also
    1. Infectious Causes of Neutropenia
    2. Drug-Induced Agranulocytosis
    3. Neutropenia
    4. Leukopenia
    5. Neutrophil
  2. Causes: Decreased Neutrophil Production
    1. Marrow Infiltration
      1. Leukemia
      2. Myelodysplastic Syndrome
      3. Myelofibrosis (tumor invasion)
      4. Granulomatous infiltration (e.g. Tuberculosis)
    2. Marrow Injury
      1. Radiation
      2. Aplastic Anemia
      3. Paroxysmal Nocturnal Hemoglobinuria
      4. Medications
        1. See Drug-Induced Agranulocytosis
      5. Infection
        1. See Infectious Causes of Neutropenia
  3. Causes: Increased Neutrophil Destruction
    1. Severe Sepsis (increased consumption)
    2. Antineutrophil Antibody
    3. Hypersplenism (Splenic trapping)
    4. Felty's Syndrome
    5. Systemic Lupus Erythematosus
    6. Chediak-Higashi Syndrome (rare autosomal recessive)
    7. Medications
      1. Phenylbutazone
      2. Phenothiazine
  4. Causes: Lower Clinical Significance
    1. Pseudoneutropenia (based on automated count)
    2. Maturation Defect
      1. Vitamin B12 Deficiency
      2. Folic Acid deficiency
    3. Margination (distribution)
      1. Bacterial infection (endotoxin)
      2. Hemodialysis
      3. Cardiopulmonary bypass

Navigation Tree