Etravirine

Aka: Etravirine, Intelence

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II. Indications

  1. Anti-Retroviral Therapy experienced patients
  2. Resistance (especially K103N) to first-generation NNRTI (Efavirenz or Nevirapine)

III. Class

  1. Non-Nucleoside Reverse Transcriptase Inhibitor (NNRTI)

IV. Adverse Effects

  1. See NNRTI for class related adverse effects
  2. Rash (20% of patients)
    1. Stop the agent and do not rechallenge
    2. Higher risk in women (30%) than men (18%)
    3. Risk of serious reactions (1-2%)
      1. Stevens-Johnson Syndrome
      2. Toxic Epidermal Necrolysis
      3. Eythema multiforme
  3. Nausea
  4. Peripheral Neuropathy
  5. Hypertension
  6. Hepatotoxicity
  7. Hyperlipidemia

V. Monitoring

  1. Liver Function Tests
  2. Lipid profile

VI. References

  1. (2008) Med Lett Drugs Ther 50(1288): 47-8 [PubMed]
  2. (1998) Med Lett Drugs Ther 40(1041):115 [PubMed]
  3. (2009) Treat Guidel Med Lett 7(78): 11-22 [PubMed]

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Related Studies

Cost: Medications

etravirine (on 6/22/2022 at Medicaid.Gov Survey of pharmacy drug pricing)
ETRAVIRINE 200 MG TABLET Generic $17.71 each
intelence (on 4/20/2022 at Medicaid.Gov Survey of pharmacy drug pricing)
INTELENCE 200 MG TABLET Generic $17.71 each
FPNotebook does not benefit financially from showing this medication data or their pharmacy links. This information is provided only to help medical providers and their patients see relative costs. Insurance plans negotiate lower medication prices with suppliers. Prices shown here are out of pocket, non-negotiated rates. See Needy Meds for financial assistance information. GoodRx is another tool for finding lower drug prices.

Related Topics in Pharmacology

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