III. Efficacy

  1. Good benefit in combination with 2 Nucleosides

IV. Dosing

  1. Start: 200 mg PO qd for 14 days
  2. If no rash, increase dose to 200 mg PO bid

V. Adverse effects

  1. See NNRTI for class related adverse effects
  2. Severe hepatoxicity and liver failure risk if pre-treatment CD4 >250 in men or >400 in women

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