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Tenofovir
Aka: Tenofovir, Viread, TDF
- See Also
- Anti-Retroviral Therapy
- Nucleoside Reverse Transcriptase Inhibitor
- Mechanism
- Nucleoside Reverse Transcriptase Inhibitor
- Adverse Effects
- See nRTI for adverse effects attributed to the class
- Renal dysfunction
- Increased Serum Creatinine
- Proteinuria
- Electrolyte abnormalities
- Glycosuria
- Hypophosphatemia
- Acute Renal Failure (1% risk)
- Associated with longer duration of therapy, advanced HIV or pre-existing renal disease
- Gastrointestinal
- Diarrhea
- Nausea or Vomiting
- Flatulence
- Miscellaneous
- Headache
- Hepatitis B flares on withdrawal of medication
- Dosing
- Dose: 300 mg orally daily
- References
- (2009) Treat Guidel Med Lett 7(78): 11-22
- Reust (2011) Am Fam Physician 83(12): 1443-51