II. Pathophysiology

  1. Edematous State reduces effective circulating volume
  2. Decreased flow to nephron diluting segment
  3. Stimulates ADH release

III. Causes

VI. Management

  1. See Hyponatremia Management
  2. Salt and water restriction
  3. Optimize Cardiac Output
  4. Consider Dialysis for Renal Insufficiency
  5. Consider Diuretics

VII. References

  1. Kone in Tisher (1993) Nephrology, p. 87-100
  2. Levinsky in Wilson (1991) Harrison's IM, p. 281-84
  3. Rose (1989) Acid-Base and Electrolytes, p. 601-38
  4. Braun (2015) Am Fam Physician 91(5): 299-307 [PubMed]

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