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Adalimumab
Aka: Adalimumab, Humira
- See Also
- Etanercept (Enbrel)
- Infliximab (Remicade)
- Indications
- Severe active Rheumatoid Arthritis refractory to DMARDs
- Contraindications
- Chronic or acute infection
- Concurrent use of Interleukin-1 Receptor Antagonist
- Anakinra (Kineret)
- Mechanism: Monoclonal Antibody
- Human antitumor Necrosis Factor alpha
- Similar to Infliximab and Etanercept
- Dosing
- Every other week: 40 mg SC
- Adverse Effects
- Immunosuppression
- Use caution in any patient prone to infection
- Headache
- Rash
- Hypertension
- Hyperlipidemia
- Injection site inflammation
- Gastrointestinal upset
- Cost
- Two 40 mg vials: $1200 (in 2003)
- References
- (2003) Lexi-Comp Drug Database