Mental Health Book

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Ziprasidone

Aka: Ziprasidone, Geodon
  1. Indications
    1. Schizophrenia (including acute episodic agitation)
    2. Mania
    3. Bipolar Disorder
    4. Tourette's Syndrome (not FDA approved)
  2. Class
    1. Atypical Antipsychotic (Second Generation agent)
  3. Advantages
    1. Minimal weight gain than with other atypical Antipsychotics
    2. Lower risk of diabetes than with other atypical Antipsychotics
  4. Drug Interactions
    1. Increase Antipsychotic levels (toxicity risk): Monitor for toxicity
      1. Clarithromycin
      2. Erythromycin
      3. Grapefruit juice
      4. Fluconazole
      5. Itraconazole
      6. Ketoconazole
    2. Decrease Antipsychotic levels (lower efficacy)
      1. Carbamazepine
      2. Phenytoin
  5. Monitoring
    1. See Antipsychotics

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