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Ergotism

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  1. History
    1. Seen in epidemic form since the Middle Ages
    2. Implicated in alleged behavior of Salem witches
  2. Causes
    1. Excessive Ergot alkaloid drug intake
      1. Ergotamine
      2. Ergonovine
      3. Methylergometrine (Methergine)
      4. Methysergide (Sansert)
      5. Bromocriptine (Parlodel)
    2. Ergot alkaloid used concurrently with potentiator
      1. Azithromycin
    3. Rye or wheat infected with fungus Claviceps purpurea
  3. Symptoms
    1. Colic
    2. Diarrhea
    3. Paresthesias
    4. Pruritus
    5. Seizures
    6. Headache
    7. Drowsiness
    8. Nausea or Vomiting
  4. Signs: Gangrene of poorly vascularized distal structures
    1. Tip of nose
    2. Ears
    3. Fingers
    4. Toes

Ergotism (C0014714)

Definition (MSH)Poisoning caused by ingesting ergotized grain or by the misdirected or excessive use of ergot as a medicine.
ConceptsInjury or Poisoning (T037)
EnglishErgot causing toxic effect, ERGOT POIS, Ergot Poisoning, Ergot Poisonings, Ergotism, Ergotisms, POIS ERGOT, SAINT ANTHONY FIRE, Saint Anthony's Fire, Saint Anthonys Fire, St. Anthony Fire, St. Anthony's Fire, St. Anthonys Fire
Spanishergotismo
CreditsDerived from the NIH UMLS (Unified Medical Language System)



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