Pulmonology Book

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Chronic Cough Causes

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  1. See Also
    1. Chronic Cough
  2. Common Causes (represents 90% of Chronic Cough causes)
    1. Post-nasal drainage (40%)
      1. Sinusitis
      2. Allergic Rhinitis
    2. Asthma (24%)
    3. Gastroesophageal Reflux (15%)
    4. Bronchitis or post-bronchitic Cough (11%)
    5. Chronic Bronchitis (Tobacco abuse)
    6. Transient airway hyperresponsiveness
      1. Post-viral cough
      2. Post-bronchitic cough
    7. Medication related
      1. ACE Inhibitors (5-20% of patients)
      2. Beta Blockers (less common)
    8. Infection
      1. Bordetella pertussis infection
  3. Less Common Causes of Chronic Cough
    1. Congestive Heart Failure
    2. Cancer
      1. Bronchogenic carcinoma
      2. Esophageal Cancer
    3. Interstitial Lung Disease
      1. Emphysema
      2. Sarcoidosis
    4. Bronchiectasis (4%)
    5. Eosinophilic Bronchitis
    6. Tuberculosis
    7. Sarcoidosis
    8. Fungal lung infection
    9. Cystic Fibrosis
    10. Recurrent Aspiration
      1. Post-Cerebrovascular Accident
      2. Frequent Vomiting
      3. Alcoholism
    11. Pressure from an intrathoracic mass
      1. Thoracic aneurysm
      2. Thyromegaly
      3. Mediastinal Lymphadenopathy
    12. Irritation of cough receptors in ear
      1. Impacted cerumen or hair in ear canal
      2. Hair
      3. Ear Foreign Body
    13. Opportunistic infections (immunocompromised patient)
    14. Lymphangitis carcinomatosis
    15. Foreign body
    16. Chronic occupational inhalation bronchial irritants
    17. Psychogenic cough (Habit Cough)
  4. References
    1. Palombini (1999) Chest 116:279
    2. Irwin (2000) N Engl J Med 343:1715

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