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Bronchiolitis Obliterans with Organizing PneumoniaAka: BOOP, Cryptogenic Organizing Pneumonitis, COP

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  1. See Also
    1. Bronchiolitis Obliterans
  2. Causes
    1. Similar list of causes as Bronchiolitis Obliterans
    2. Idiopathic form: Cryptogenic Organizing Pneumonia
  3. Presentation
    1. Slowly resolving Pneumonia over weeks to months
      1. Consider in unresolved community acquired Pneumonia
    2. May be associated with fever and Sore Throat
  4. Symptoms
    1. Non-productive cough
    2. Dyspnea
  5. Signs
    1. Diffuse rales
    2. Rare Wheezes
  6. Imaging: Chest XRay
    1. Variable appearance (may be normal)
    2. Bilateral ground glass, patchy appearance (most common)
    3. Diffuse nodular pattern
  7. Diagnostics
    1. Arterial Blood Gas or Oxygen Saturation
      1. Hypoxemia in most patients
    2. Pulmonary Function Tests
      1. Restrictive lung disease
      2. DLCO decreased

Bronchiolitis Obliterans Organizing Pneumonia (C0242770)

Definition (MSH)A disease formerly considered a form of interstitial pneumonia. Its etiology is obscure but it may be associated with toxic fumes, infection, and connective tissue disease. Clinical symptoms include cough, dyspnea and influenza-like symptoms with the development of the usual interstitial pneumonia in many cases. Obstructive symptoms are limited to smokers. There are patchy polypoid masses of intra-alveolar granulation tissue in small airway lumina and alveolar ducts. "Organizing" refers to unresolved pneumonia (in which the alveolar exudate persists and eventually undergoes fibrosis) in which fibrous tissue forms in the alveoli. (From Segen, Dictionary of Modern Medicine, 1992; Stedman, 25th ed)
Definition (NCI)A disease formerly considered a form of interstitial pneumonia. Its etiology is obscure but it may be associated with toxic fumes, infection, and connective tissue disease. Clinical symptoms include cough, dyspnea and influenza-like symptoms with the development of the usual interstitial pneumonia in many cases. Obstructive symptoms are limited to smokers. There are patchy polypoid masses of intra-alveolar granulation tissue in small airway lumina and alveolar ducts. "Organizing" refers to unresolved pneumonia (in which the alveolar exudate persists and eventually undergoes fibrosis) in which fibrous tissue forms in the alveoli.
ConceptsDisease or Syndrome (T047)
MSHD018549
EnglishBOOP, BOOP - Bronchiolitis obliterans and organising pneumonitis, BOOP - Bronchiolitis obliterans and organizing pneumonitis, Bronchiolitis obliterans and organising pneumonitis, Bronchiolitis obliterans and organizing pneumonitis, Bronchiolitis obliterans organising pneumonia, Bronchiolitis Obliterans Organizing Pneumonia, Bronchiolitis obliterans with organising pneumonia, Bronchiolitis obliterans with organizing pneumonia, COP, COP - Cryptogenic organising pneumonitis, COP - Cryptogenic organizing pneumonitis, Cryptogenic organising pneumonia, Cryptogenic organising pneumonitis, Cryptogenic organizing pneumonia, Cryptogenic organizing pneumonitis
Spanishbronquiolitis obliterante con neumonia en desarrollo, bronquiolitis obliterante y neumonia con organizacion, neumonia criptogena en desarrollo
Parent ConceptsBronchiolitis Obliterans (C0006272), Pneumonia (C0032285), Hamman-Rich syndrome (C0085786)
SourcesMSH, MTH, NCI, NDFRT, SCTSPA, SNOMEDCT
Derived from the NIH UMLS (Unified Medical Language System)



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