Hematology and Oncology Book

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Deep Vein Thrombosis of the Upper Extremity

Aka: Deep Vein Thrombosis of the Upper Extremity, Upper Extremity DVT
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  1. See Also
    1. Deep Vein Thrombosis
  2. Causes
    1. Central Venous Catheter (common)
    2. External Vein Compression (Effort Thrombosis)
      1. Athletes with muscle hypertrophy
    3. Idiopathic (rare)
      1. Evaluate for occult cancer
      2. Consider evaluation for Hypercoagulable state
  3. Symptoms
    1. Shoulder or Neck Pain
    2. Edema of the hand or arm
  4. Signs
    1. Arm with palpable cord
    2. Supraclavicular fullness
    3. Cyanosis of extremity
    4. Venous distention
      1. Superficial vein distention
      2. Jugular Venous Distention
  5. Differential Diagnosis
    1. Thoracic Outlet Syndrome
  6. Radiology
    1. Duplex Ultrasound of upper extremity
  7. Management
    1. Anticoagulation with Warfarin (Coumadin)
      1. Low Molecular Weight Heparin until INR therapeutic
    2. Consider catheter directed Thrombolysis
  8. Complications
    1. Pulmonary Embolism (33% of cases)
    2. Superior Vena Cava Syndrome
  9. References
    1. Joffe (2002) Circulation 106:1874-80

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