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Subacute Lymphocytic Thyroiditis

Aka: Subacute Lymphocytic Thyroiditis, Silent Sporadic Thyroiditis, Painless Sporadic Thyroiditis
  1. Pathophysiology
    1. Autoimmune lymphocytic infiltrate
  2. Epidemiology
    1. More common in women by 4 fold
  3. Signs
    1. Goiter (50%)
    2. Hyperthyroidism (up tp 20%)
      1. Duration: Typically <4 months
      2. Followed by Hypothyroidism and then euthyroid
  4. Differential Diagnosis
    1. Postpartum Thyroiditis
      1. Nearly identical, except limited to postpartum period
    2. Hashimoto's Thyroiditis
      1. Similar, except pathology (Fibrosis, Hurthle Cells)
    3. Grave's Disease
      1. Presents with pretibial edema, Proptosis
    4. Subacute Thyroiditis
      1. Painful Thyroiditis
  5. Labs
    1. Thyroid Function Tests (T4 Free and TSH)
    2. Antibodies
      1. Antithyroid Peroxidase Antibody (positive in 50%)
      2. Thyroid Stimulating Immunoglobulins absent
        1. Contrast with Grave's Disease
  6. Imaging
    1. Radioiodine Uptake (Thyroid uptake and scan)
      1. Low uptake (contrast with Grave's Disease)
  7. Course
    1. Resolves within 1 year in most cases
  8. References
    1. Bindra (2006) Am Fam Physician 73(10):1769-76

Subacute lymphocytic thyroiditis (C1306804)

Concepts Disease or Syndrome (T047)
SnomedCT 361126006, 18018005
English Subacute lymphocytic thyroiditis, Subacute lymphocytic thyroiditis (disorder), Subacute Lymphocytic Thyroiditis
Spanish tiroiditis linfocítica subaguda (trastorno), tiroiditis linfocítica subaguda
Sources
Derived from the NIH UMLS (Unified Medical Language System)


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