II. Staging: NYHA Classification

  1. Class I: Symptoms with more than ordinary activity
  2. Class II: Symptoms with ordinary activity
  3. Class III: Symptoms with minimal activity
    1. Class IIIa: No Dyspnea at rest
    2. Class IIIb: Recent Dyspnea at rest
  4. Class IV: Symptoms at rest

III. Staging: Alternative Heart Failure classification

  1. Asymptomatic (NYHA Class I)
  2. Symptomatic (NYHA Class II and Class III)
  3. Symptomatic with recent Dyspnea at rest (Class IIIb)
  4. Symptomatic with Dyspnea at rest (Class IV)

IV. Staging: AHA Heart Failure Stage

  1. Stage A
    1. No symptoms
    2. No heart disease
    3. Heart Failure risk factors
      1. Hypertension
      2. Diabetes Mellitus or Metabolic Syndrome
      3. Obesity
      4. Atherosclerotic disease
      5. Cardiomyopathy risks (e.g. cardiotoxin exposure, Family History)
  2. Stage B
    1. No symptoms
    2. Structural heart disease
      1. History of Myocardial Infarction
      2. Valvular heart disease (asymptomatic)
      3. Left Ventricular Hypertrophy or other evidence of remodeling
      4. Decreased ejection fraction
  3. Stage C
    1. Heart Failure symptoms
    2. Structural heart disease
  4. Stage D
    1. Symptoms requiring aggressive medical management
    2. Advanced structural heart disease

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Ontology: New York Heart Association Class (C1882083)

Definition (NCI) Defined as patients with defined or presumed cardiac disease and one of the following: Class I: without limitations of physical activity. Ordinary physical activity does not cause undue fatigue, palpitation, or dyspnea. Class II: slight limitation of physical activity. They are comfortable at rest. Ordinary physical activity results in fatigue, palpitation, or dyspnea. Class III: marked limitation of physical activity. They are comfortable at rest. Less than ordinary activity causes fatigue, palpitation, or dyspnea. Class IV: inability to carry on any physical activity without discomfort. Symptoms are present even at rest or minimal exertion. (The Criteria Committee of the New York Heart Association. Nomenclature and Criteria for Diagnosis of Diseases of the Heart and Great Vessels. 9th ed. Boston, Mass: Little, Brown & Co; 1994:253-256.)(NIH Roadmap Cardiovascular Data Standards Working Group)
Definition (NCI) A finding associated with a patient based on the functional classification developed by the New York Heart Association (NYHA), for categorizing patients with defined or presumed cardiac disease. The classification system is based on the ability, or lack thereof, to engage in physical activity. The classification system comprises four classes, though NYHA Class III and Class IV are often aggregated for the purpose of outcomes analysis.
Definition (NCI_CDISC) A finding associated with a patient based on the functional classification developed by the New York Heart Association (NYHA), for categorizing patients with defined or presumed cardiac disease. The classification system is based on the ability to engage in physical activity. The classification system comprises four classes, though NYHA Class III and Class IV are often aggregated for the purpose of outcomes analysis.
Concepts Finding (T033)
English NYHA Class, New York Heart Association Class, NYHACLS