Prevention Book

http://www.fpnotebook.com/

Family HistoryAka: Pedigree

Advertisement

  1. Percentage of shared genes among relatives
    1. First Degree Relatives share 50% of genes
      1. Children
      2. Parents
      3. Siblings
    2. Second Degree Relatives share 25% of genes
      1. Aunts and Uncles
      2. Neices and nephews
      3. Grandparents
      4. Half-siblings
    3. Third Degree Relatives share 12.5% of genes
      1. First Cousins
      2. Great Grandparents
  2. Quick Family History for common diseases
    1. Coronary Artery Disease
    2. Cerebrovascular Accident
    3. Diabetes Mellitus
    4. Breast Cancer
    5. Ovarian Cancer
    6. Colon Cancer
  3. Single Gene Diseases
    1. Hemochromatosis (HFE)
    2. Tuberous Sclerosis (TS1, TS2)
    3. Autosomal Dominant Polycystic Kidney Disease (ADPKD1-2)
    4. Hereditary Hemorrhagic Telangiectasia (ENG, ACVRL1)
    5. Idiopathic Pulmonary Hypertension (BMPR2)
    6. Long QT Syndrome
    7. Factor V Leiden or APC Resistance
    8. Alpha-1-Antitrypsin Deficiency (SERPINA)
    9. Glaucoma (MYOC)
    10. Hereditary Pancreatitis (PTSS1)
  4. Resources
    1. U.S. Surgeon General's Family History Initiative
      1. http://www.hhs.gov/familyhistory
  5. References
    1. Wattendrof (2005) Am Fam Physician 72(3):441

genetic pedigree (C0030761)

Definition (MSH)The record of descent or ancestry, particularly of a particular condition or trait, indicating individual family members, their relationships, and their status with respect to the trait or condition.
Definition (NCI)A record of one's ancestors, offspring, siblings, and their offspring that may be used to determine the pattern of certain genes or disease inheritance within a family.
Definition (NCI)A record of descent or ancestry, particularly of a particular condition or trait, indicating individual family members, their relationships, and their status with respect to the trait or condition. (from MeSH)
ConceptsIntellectual Product (T170)
EnglishGenealogical Tree, genetic pedigree, Pedigree
CreditsDerived from the NIH UMLS (Unified Medical Language System)


Family history of (C0241889)

Definition (NCI)A record of a patient's background regarding health and disease events of blood relatives. A patients family medical history may be important in diagnosing existing conditions. (NCI)
ConceptsFinding (T033)
EnglishFamily health history, FAMILY HISTORY, Family history of, Family history of clinical finding, Family medical history, FH
Spanishantecedente familiar de hallazgo clínico, antecedente familiar de hallazgo clinico, antecedentes familiares, antecedentes familiares de, antecedentes familiares relacionados con la salud, antecedentes familiares: SAI, antecedentes médicos familiares, antecedentes medicos familiares, historia familiar
CreditsDerived from the NIH UMLS (Unified Medical Language System)



Navigation Tree