II. Epidemiology: Percentage of shared genes among relatives

  1. First Degree Relatives share 50% of genes
    1. Children
    2. Parents
    3. Siblings
  2. Second Degree Relatives share 25% of genes
    1. Aunts and Uncles
    2. Neices and nephews
    3. Grandparents
    4. Half-siblings
  3. Third Degree Relatives share 12.5% of genes
    1. First Cousins
    2. Great Grandparents

IV. Associated Conditions: Single Gene Diseases

V. Resources

  1. U.S. Surgeon General's Family History Initiative
    1. http://www.hhs.gov/familyhistory

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Ontology: genetic pedigree (C0030761)

Definition (NCI_NCI-GLOSS) A diagram that shows relationships among family members. In medicine, a pedigree may also show the pattern of certain genes or diseases within a family.
Definition (NCI) A record of descent or ancestry, particularly of a specific condition or trait, indicating individual family members, their relationships, and their status with respect to the trait or condition.
Definition (MSH) The record of descent or ancestry, particularly of a particular condition or trait, indicating individual family members, their relationships, and their status with respect to the trait or condition.
Concepts Intellectual Product (T170)
MSH D010375
English Pedigree, pedigrees, family tree, pedigree, Genealogical Tree, genetic pedigree
Swedish Stamtavla
Czech rodokmen
Finnish Sukupuu
Russian GENEALOGICHESKOE DEREVO, GENEALOGIIA, ГЕНЕАЛОГИЧЕСКОЕ ДЕРЕВО, ГЕНЕАЛОГИЯ
Japanese 系図, 家系図, 血統
Polish Rodowód
French Pedigree
Portuguese Pedigree, Linhagem
German Stammbaum
Italian Pedigree
Dutch Afkomst, Stamboom
Spanish Linaje

Ontology: Family history (C0241889)

Definition (MEDLINEPLUS)

Your family history includes health information about you and your close relatives. Families have many factors in common, including their genes, environment, and lifestyle. Looking at these factors can help you figure out whether you have a higher risk for certain health problems, such as heart disease, stroke, and cancer.

Having a family member with a disease raises your risk, but it does not mean that you will definitely get it. Knowing that you are at risk gives you a chance to reduce that risk by following a healthier lifestyle and getting tested as needed.

You can get started by talking to your relatives about their health. Draw a family tree and add the health information. Having copies of medical records and death certificates is also helpful.

Centers for Disease Control and Prevention

Definition (NCI) A record of a patient's background regarding health and disease events of blood relatives. A patient's family medical history may be important in diagnosing existing conditions.
Definition (NCI_NCI-GLOSS) A record of the relationships among family members along with their medical histories. This includes current and past illnesses. A family history may show a pattern of certain diseases in a family.
Concepts Finding (T033)
SnomedCT 57177007, 266909004, 137667000, 276502004, 160470003, 137863003
English FH: NOS, Family health history, Family history of (contextual qualifier) (context-dependent category), Family history: NOS (context-dependent category), family history, family history (history), free text for family history (history), free text for family history, family history free text, Family history with explicit context, Family history with explicit context (situation), Family history of (contextual qualifier) (situation), Family history of, Family history of (contextual qualifier), family history of, fhs, fh, of family history, Family history, Family History, Family health history (context-dependent category), Family history (situation), Family history: NOS, Family history: NOS (situation), FH: NOS (situation), family medical history, FH, FH - Family history, Family health history (finding), Family Medical History, Epidemiology, Family Medical History, Family History of
Spanish antecedente familiar, SAI (categoría dependiente del contexto), antecedentes familiares de (categoría dependiente del contexto), antecedentes familiares relacionados con la salud, antecedentes familiares de (situación), antecedentes familiares, historia familiar, antecedentes familiares de, antecedente familiar con contexto explícito, antecedente familiar con contexto explícito (situación), antecedente familiar de (calificador de contexto) (situación), antecedente familiar de (calificador de contexto), antecedente familiar, SAI, antecedente familiar, SAI (situación), antecedentes médicos familiares, FH: NOS, antecedentes médicos familiares (hallazgo), antecedentes familiares: SAI (categoría dependiente del contexto), antecedentes familiares: SAI, antecedentes familiares relacionados con la salud (hallazgo)