Skin Lesion Solid White

Aka: Skin Lesion Solid White, Hypopigmentation, Hypomelanosis

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II. Causes: Patches or Plaques (Hypopigmentation)

  1. Pityriasis Alba
  2. Pityriasis Versicolor (Tinea Versicolor)
  3. Vitiligo
  4. Postinflammatory Hypopigmentation
  5. Cryotherapy
  6. Hypopigmented Mycosis Fungoides (cutaneous T Cell Lymphoma)
    1. Mycosis Fungoides variant found in children
    2. Hypopigmented nonatrophic patches with fine scale, found on the trunk, buttocks and extremities
  7. Corticosteroids
    1. Associated with prolonged potent Topical Corticosteroids, intraarticular or intradermal Corticosteroid Injections
    2. Hypopigmented patches with irregular borders
  8. Chemical Leukoderma
    1. Hypomelanosis due to chemical contact exposure (e.g. phenols, catechols)
    2. Household disinfectants and detergents
    3. Hydroquinone
    4. P-phenylenediamine (hair dyes)
    5. Chloroquine
    6. Tretinoin
    7. Metals (e.g. Arsenic, mercurials)

III. Causes: Papules

  1. Milia
  2. Keratosis Pilaris
  3. Molluscum Contagiosum

IV. Causes: Diffuse changes (congenital conditions, uncommon)

  1. Albinism
  2. Piebaldism
  3. Tuberous sclerosis
  4. Hypermelanosis of Ito

V. References

  1. Chiakpo (2022) Am Fam Physician 106(5): 573-4 [PubMed]

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