II. Epidemiology

  1. Incidence: 40-50% of newborns

III. Pathophysiology

  1. Superficial inclusion cysts due to retention of keratin (Keratin Cysts)

IV. Signs

  1. Flat, whitish Papules, 1-2 mm in diameter
  2. Distribution
    1. Face is most typical (Forehead, cheeks, nose, chin)
    2. Other areas: Upper trunk, extremities and penis
    3. Oral Mucosa (Epstein's Pearls)
  3. Timing
    1. Resolve spontaneously after 3-4 weeks

V. Management

  1. None needed
  2. Spontaneously resolve within first few months of life

VI. References

  1. Claudius and Behar in Herbert (2020) EM:Rap 20(8): 5-7

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