II. Epidemiology

  1. Nitrous Abuse is common among (esp. dentists, anesthesia professionals, as well as teens)

III. Pathophysiology

  1. Nitrous Oxide is widely used in dental anesthesia and in food industry (Whippets)

IV. Symptoms

  1. Euphoria
  2. Dissociation
  3. Analgesia

V. Adverse Effects

  1. Hypoxia
  2. Nausea
  3. Trauma from Loss of Consciousness (i.e. falls)
  4. Nitrous Induced Subacute Combined Degeneration of the Spinal Cord
    1. Nitrous Oxide inhalation interferes with Vitamin B12 Metabolism
    2. Results in Vitamin B12 Deficiency with secondary long segmental changes involving the Posterior Columns

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Ontology: Intentional nitrous oxide overdose (C0572389)

Concepts Injury or Poisoning (T037)
SnomedCT 295499002
English Intentional nitrous oxide OD, Intentional nitrous oxide overdose, Intentional nitrous oxide overdose (disorder)
Spanish sobredosis voluntaria de óxido nitroso (trastorno), sobredosis voluntaria de óxido nitroso