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StrongyloidesAka: Strongyloides stercoralis
- Classification
- Nematode: Roundworm
- Epidemiology
- Responsible for most U.S. cases fatal Helminth disease
- Endemic areas
- Tropical Asia
- Sub-Saharan Africa
- Latin America
- Pockets in Rural southeastern United States
- Pockets in Eastern Europe
- Risk factors for Hyperinfection (Immunocompromised)
- Chronic Corticosteroid use
- Chemotherapy
- Human Immunodeficiency Virus (HIV)
- Differential Diagnosis
- Symptoms
- Often asymptomatic
- Larva currens
- Recurrent serpiginous Urticaria
- Onset in perianal area
- Migratory rash to buttocks, groin, trunk
- Gastrointestinal side effects
- Abdominal Pain or abdominal bloating
- Diarrhea
- Pulmonary involvement
- Labs
- Eosinophilia in stool
- Guaiac-positive stools
- Rhabditiform larvae present in sample
- Stool sample or duodenal aspiration
- False negative test: 70% of cases
- Management
- Ivermectin (now preferred agent)
- Better tolerated than Thiabendazole
- Higher cure rate than Thiabendazole
- Other agents
- Thiabendazole
- Albendazole
- Ivermectin (now preferred agent)
- Prognosis
- Hyperinfection mortality rate in immunosuppressed: 87%
- References
Strongyloides (C0038461) | |
|---|---|
| Definition (MSH) | A genus of parasitic nematodes widely distributed as intestinal parasites of mammals. |
| Concepts | Invertebrate (T009) |
| MSH | D013321 |
| English | Strongyloides |
| Parent Concepts | Nematoda (C0027581), Rhabdiasoidea (C0035407), Strongyloididae (C0997974), Intestinal nematode (C0446312) |
| Sources | AOD, COSTAR, CSP, MSH, NCBI, SCTSPA, SNOMEDCT Derived from the NIH UMLS (Unified Medical Language System) |