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Direct Coombs
Aka: Direct Coombs, Direct Antiglobulin Test, DAT- See Also
- Coombs (describes testing methodology and background)
- Normal
- Negative
- Positive
Alzheimer's Disease (C0002395) |
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| Definition (MEDLINEPLUS) |
Alzheimer's disease (AD) is the most common form of dementia among older people. Dementia is a brain disorder that seriously affects a person's ability to carry out daily activities. AD begins slowly. It first involves the parts of the brain that control thought, memory and language. People with AD may have trouble remembering things that happened recently or names of people they know. Over time, symptoms get worse. People may not recognize family members or have trouble speaking, reading or writing. They may forget how to brush their teeth or comb their hair. Later on, they may become anxious or aggressive, or wander away from home. Eventually, they need total care. This can cause great stress for family members who must care for them. AD usually begins after age 60. The risk goes up as you get older. Your risk is also higher if a family member has had the disease. No treatment can stop the disease. However, some drugs may help keep symptoms from getting worse for a limited time. NIH: National Institute on Aging |
| Definition (NCI) | A brain disorder that usually starts in late middle age or old age and gets worse over time. Symptoms include loss of memory, confusion, difficulty thinking, and changes in language, behavior, and personality. |
| Definition (JABL) | A disabling degenerative disease of the nervous system occurring in middle-aged or older persons and characterized by dementia and failure of memory for recent events, followed by total incapacitation and death. Types of the Alzheimer syndrome are differentiated by the age of onset and genetic characteristics. The early onset form (the mean age of the onset of symptoms between the ages of 40 and 60 years) and the late onset form (the onset of symptoms after the age of 60 years). Three forms are identified: AD-1, AD-2, AD-3. Some of the clinical characteristics of the Alzheimer syndrome are similar to those of the Pick syndrome. |
| Definition (MSH) | A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57) |
| Definition (NCI) | A progressive, neurodegenerative disease characterized by loss of function and death of nerve cells in several areas of the brain leading to loss of cognitive function such as memory and language. |
| Definition (CSP) | neurodegenerative disorder of the CNS resulting in progressive loss of memory and intellectual functions; begins in the middle or later years; characterized by brain lesions such as neurofibrillary tangles and neuritic plaques. |
| Concepts | Disease or Syndrome (T047) |
| MSH | D000544 |
| ICD9 | 331.0 |
| ICD10 | G30, F00, F00.9, G30.9 |
| SnomedCT | 73768007, 26929004, 192164001, 192160005, 154998003, 267688001 |
| English | PRIMARY DEGENERATIVE DEMENTIA, Alzheimer Disease, Alzheimer's Disease, Alzheimers Disease, Dementia, Senile, Dementias, Senile, Disease, Alzheimer, Disease, Alzheimer's, Senile Dementias, ALZHEIMER'S DISEASE, DAT, DEMENTIA OF THE ALZHEIMER TYPE, SDAT, SENILE DEMENTIA OF THE ALZHEIMER TYPE, Senile Dementia, Alzheimer's disease, NOS, Alzheimer's disease unspec, DAT - Dementia Alzheimer type, DAT - Dementia Alzheimer's type, Dementia in Alzheimer's dis, Dementia in Alzheimer's disease, Dementia in Alzheimer's disease, unspecified, [X]Alzheimer's disease unspec, [X]Dementia in Alzheimer's disease, unspecified, Alzheimer's disease, unspecified, Alzheimer's Dementia, AD, ALZHEIMER DISEASE, ALZHEIMER DIS, ALZHEIMERS DIS, [X]Dementia in Alzheimer's, [X]Dementia in Alzheimer's disease, Dementia in Alzheimer's, primary degenerative dementia, Alzheimer's dementia, dementia of Alzheimer's type (diagnosis), simple senile dementia, dementia of Alzheimer's type, Alzheimer's dementia (diagnosis), alzheimer's disease, Dementia of the Alzheimer's type NOS, DEMENTIA ALZHEIMER, DEMENTIA PRIMARY DEGENERATIVE, Alzheimer Type Senile Dementia, Senile Dementia, Alzheimer Type, Alzheimer Type Dementia, Dementia, Alzheimer Type, [X]Dementia in Alzheimer's disease, unspecified (disorder), [X]Dementia in Alzheimer's disease (disorder), Alzheimer dementia (AD), Alzheimer disease (AD), Alzheimer-type dementia (ADT), dementia of the Alzheimer type (DAT), senile dementia of the Alzheimer type (SDAT), senile dementia of the Alzheimer type, Alzheimer-type dementia, dementia of the Alzheimer type, Alzheimer sclerosis, Alzheimer syndrome, Alzheimer disease, Alzheimer Disease [Disease/Finding], alzheimers disease, dats, senile dementia, Alzheimers dementia, Disease;Alzheimers, alzheimer diseases, alzheimer's diseases, dementia alzheimers, Alzheimer dementia, Dementia, Primary Senile Degenerative, Dementia Alzheimer's type, Alzheimer's disease, AD - Alzheimer's disease, Alzheimer's disease (disorder), Alzheimer; dementia (etiology), Alzheimer; dementia (manifestation), Alzheimer; sclerosis, Alzheimer, dementia; Alzheimer (etiology), dementia; Alzheimer (manifestation), dementia; primary degenerative, primary; degenerative, dementia, sclerosis; Alzheimer, Dementia of Alzheimers Type, Dementia of the Alzheimer's type, Primary Senile Degenerative Dementia, alzheimers dementia, Alzheimers disease |
| Portuguese | DOENCA DE ALZHEIMER, Demência tipo Alzheimer NE, Demência de tipo Alzheimer, Demência Senil, Demência Senil Tipo Alzheimer, Demência Tipo Alzheimer, Doença de Alzheimer |
| Spanish | ENFERMEDAD DE ALZHEIMER, Demencia de tipo Alzheimer NEOM, Alzheimer's disease, [X]demencia en la enfermedad de Alzheimer, no especificada, [X]demencia en la enfermedad de Alzheimer (trastorno), [X]demencia en la enfermedad de Alzheimer, demencia en la enfermedad de Alzheimer, [X]demencia en la enfermedad de Alzheimer, no especificada (trastorno), enfermedad de Alzheimer (trastorno), enfermedad de Alzheimer, Demencia de tipo Alzheimer, Enfermedad de Alzheimer, Demencia Senil, Demencia Senil Tipo Alzheimer, Demencia Tipo Alzheimer |
| Dutch | dementie van Alzheimer type NAO, ziekte van Alzheimer, Alzheimer; dementie, Alzheimer; sclerose, dementie; Alzheimer, dementie; primair degeneratief, primair; degeneratief, dementie, sclerose; Alzheimer, Dementie bij ziekte van Alzheimer, niet gespecificeerd, Ziekte van Alzheimer, niet gespecificeerd, dementie type Alzheimer, Dementie bij ziekte van Alzheimer, Dementie, Alzheimer-type, Dementie, seniele, Seniele dementie, Alzheimer-type, Ziekte van Alzheimer |
| French | Démence de type Alzheimer SAI, MALADIE D'ALZHEIMER, Démence de type Alzheimer, Démence d'Alzheimer, Maladie d'Alzheimer, Démence dégénérative primaire de type Alzheimer, Démence sénile primitive de type Alzheimer, Démence sénile primitive dégénérative |
| German | Demenz vom Alzheimer Typ NNB, ALZHEIMERSCHE ERKRANKUNG, Alzheimer-Krankheit, nicht naeher bezeichnet, Demenz bei Alzheimer-Krankheit, nicht naeher bezeichnet, Demenz bei Alzheimer-Krankheit, Demenz vom Alzheimertyp, Alzheimer-Krankheit, Dementia senilis, Demenz, senile, Demenz, Alzheimer-Typ, Senile Demenz, Alzheimer-Typ, Demenz, primär degenerative senile, Primär degenerative senile Demenz |
| Italian | Demenza tipo Alzheimer NAS, Demenza tipo Alzheimer, Demenza senile tipo Alzheimer, Demenza senile, Demenza degenerativa primaria senile, Malattia di Alzheimer |
| Japanese | アルツハイマー型認知症ＮＯＳ, ｱﾙﾂﾊｲﾏｰｶﾞﾀﾆﾝﾁｼｮｳ, ｱﾙﾂﾊｲﾏｰｶﾞﾀﾆﾝﾁｼｮｳNOS, ｱﾙﾂﾊｲﾏｰﾋﾞｮｳ, Alzheimer型認知症, 初老期認知症-Alzheimer型, アルツハイマー型認知症, アルツハイマー型老年痴呆, 痴呆-アルツハイマー型, アルツハイマー型痴呆-初老期, 老年期認知症-Alzheimer型, Alzheimer型痴呆, 初老期アルツハイマー型痴呆, アルツハイマー病, 認知症-Alzheimer型, アルツハイマー型初老期痴呆, 老年一次性変性痴呆, アルツハイマー型痴呆, 初老期痴呆-Alzheimer型, 老年期痴呆-アルツハイマー型, 一次痴呆, 急性錯乱性老年性痴呆, 初老期痴呆-アルツハイマー型, 痴呆-一次性変性-老年, 老年期痴呆-Alzheimer型, Alzheimer型老年期痴呆, アルツハイマー型老年期痴呆, 痴呆-Alzheimer型, Alzheimer病, Alzheimer型初老期痴呆 |
| Swedish | Alzheimers sjukdom |
| Czech | Alzheimerova nemoc, Demence Alzheimerova typu, Demence Alzheimerova typu NOS |
| Finnish | Alzheimerin tauti |
| Russian | DEMENTSIIA SENIL'NAIA, SENIL'NAIA DEMENTSIIA SO SPUTANNOST'IU SOZNANIIA, AL'TSGEIMERA BOLEZN', DEMENTSIIA PRESENIL'NAIA AL'TSGEIMERA, DEMENTSIIA TIPA AL'TSGEIMERA, АЛЬЦГЕЙМЕРА БОЛЕЗНЬ, ДЕМЕНЦИЯ ПРЕСЕНИЛЬНАЯ АЛЬЦГЕЙМЕРА, ДЕМЕНЦИЯ СЕНИЛЬНАЯ, ДЕМЕНЦИЯ ТИПА АЛЬЦГЕЙМЕРА, СЕНИЛЬНАЯ ДЕМЕНЦИЯ СО СПУТАННОСТЬЮ СОЗНАНИЯ |
| Korean | 알쯔하이머병에서의 치매, 상세불명의 알쯔하이머병에서의 치매, 알쯔하이머병, 상세불명의 알쯔하이머병 |
| Croatian | ALZHEIMEROVA BOLEST |
| Polish | Choroba Alzheimera |
| Hungarian | Alzheimer típusú dementia k.m.n., Alzheimer-kór, Alzheimer-típusú dementia |
| Sources |
Derived from the NIH UMLS (Unified Medical Language System) |