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Glucose Challenge Test

Indication: Gestational Diabetes Screening Test
1. All pregnant patients at 24-28 weeks gestation
2. Test with initial Prenatal Labs if indicated below
  1. Overweight patient
  2. Family History of Diabetes Mellitus
  3. Age over 30 years
  4. Prior history of Glucose Intolerance
  5. Prior pregnancy complication
    1. Fetal Macrosomia
    2. Intrauterine Fetal Demise (Stillborn)
    3. Pregnancy Induced Hypertension (PIH)
    4. Polyhydramnios
    5. Congenital defect
Protocol
1. Patient ingests 50 gram Glucola Drink
2. Serum Glucose measured after 1 hour
Interpretation
1. Serum Glucose >130 mg/dl suggests gestation diabetes
2. Obtain Glucose Tolerance Test 3 hour if positive
Efficacy
1. Test Sensitivity: 90% (80% if 140 mg/dl cut-off used)
2. Test Specificity: 87%
References
1. (2001) Obstet Gynecol 98:525

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This page was written by Scott Moses, MD. This page was last revised before 5/10/08, prior to consistent tracking of revision date. This page was last published on 5/16/2008. Please send comments and questions to the editor. Contact information may be found on the page About the Family Practice Notebook. These pages are best viewed with Microsoft Internet Explorer 6.0.